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发展中国家一家三级医疗中心急诊科收治的危重症新冠肺炎患者的结局:一项回顾性队列研究

Outcomes of critically ill COVID-19 patients boarding in the emergency department of a tertiary care center in a developing country: a retrospective cohort study.

作者信息

Zahran Tharwat El, Al Hassan Sally, Al Karaki Victoria, Hammoud Lina, Helou Christelle El, Khalifeh Malak, Al Hariri Moustafa, Tamim Hani, Majzoub Imad El

机构信息

Department of Emergency Medicine, American University of Beirut Medical Center, Beirut, Lebanon.

QU Health, Qatar University, Doha, Qatar.

出版信息

Int J Emerg Med. 2023 Oct 13;16(1):73. doi: 10.1186/s12245-023-00551-8.

Abstract

BACKGROUND

Boarding of critically ill patients in the emergency department (ED) has long been known to compromise patient care and affect outcomes. During the COVID-19 pandemic, multiple hospitals worldwide experienced overcrowded emergency rooms. Large influx of patients outnumbered hospital beds and required prolonged length of stay (LOS) in the ED. Our aim was to assess the ED LOS effect on mortality and morbidity, in addition to the predictors of in-hospital mortality, intubation, and complications of critically ill COVID-19 ED boarder patients.

METHODS

This was a retrospective cohort study, investigating 145 COVID-19-positive adult patients who were critically ill, required intensive care unit (ICU), and boarded in the ED of a tertiary care center in Lebanon. Data on patients who boarded in the emergency from January 1, 2020, till January 31, 2021, was gathered and studied.

RESULTS

Overall, 66% of patients died, 60% required intubation, and 88% developed complications. Multiple risk factors were associated with mortality naming age above 65 years, vasopressor use, severe COVID pneumonia findings on CT chest, chemotherapy treatment in the previous year, cardiovascular diseases, chronic kidney diseases, prolonged ED LOS, and low SaO < 95% on triage. In addition, our study showed that staying long hours in the ED increased the risk of developing complications.

CONCLUSION

To conclude, all efforts need to be drawn to re-establish mitigation strategies and models of critical care delivery in the ED to alleviate the burden of critical boarders during pandemics, thus decreasing morbidity and mortality rates. Lessons from this pandemic should raise concern for complications seen in ED ICU boarders and allow the promotion of health measures optimizing resource allocation in future pandemic crises.

摘要

背景

长期以来,人们都知道在急诊科(ED)收治重症患者会影响患者护理并影响治疗结果。在新冠疫情期间,全球多家医院的急诊室人满为患。大量患者涌入,医院床位供不应求,患者在急诊科的住院时间(LOS)延长。我们的目的是评估急诊科住院时间对死亡率和发病率的影响,以及新冠重症急诊科收治患者的院内死亡率、插管和并发症的预测因素。

方法

这是一项回顾性队列研究,调查了145名新冠病毒检测呈阳性的成年重症患者,这些患者需要重症监护病房(ICU)治疗,并被收治在黎巴嫩一家三级医疗中心的急诊科。收集并研究了2020年1月1日至2021年1月31日期间在急诊科收治的患者的数据。

结果

总体而言,66%的患者死亡,60%的患者需要插管,88%的患者出现并发症。多种风险因素与死亡率相关,包括65岁以上的年龄、使用血管加压药、胸部CT显示严重新冠肺炎、前一年接受化疗、心血管疾病、慢性肾脏疾病、急诊科住院时间延长以及分诊时低氧饱和度(SaO)<95%。此外,我们的研究表明,在急诊科停留时间过长会增加出现并发症的风险。

结论

总之,需要全力以赴重新制定缓解策略和急诊科重症护理模式,以减轻疫情期间重症收治患者的负担,从而降低发病率和死亡率。这场疫情的教训应引起人们对急诊科重症监护病房收治患者出现并发症的关注,并有助于在未来的疫情危机中推广优化资源分配的健康措施。

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