• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

单核细胞和巨噬细胞的表型与功能异质性

Phenotypic and Functional Heterogeneity of Monocytes and Macrophages.

作者信息

Hellman Lars

机构信息

Department of Cell and Molecular Biology, Uppsala University, Uppsala, The Biomedical Center, Box 596, SE-751 24 Uppsala, Sweden.

出版信息

Int J Mol Sci. 2023 Sep 25;24(19):14525. doi: 10.3390/ijms241914525.

DOI:10.3390/ijms241914525
PMID:37833973
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10572615/
Abstract

Macrophages are likely to be the first immune cells to have appeared during the evolution of multicellular organisms [...].

摘要

巨噬细胞很可能是多细胞生物进化过程中最早出现的免疫细胞[...]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90b9/10572615/115feaab17d0/ijms-24-14525-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90b9/10572615/115feaab17d0/ijms-24-14525-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90b9/10572615/115feaab17d0/ijms-24-14525-g001.jpg

相似文献

1
Phenotypic and Functional Heterogeneity of Monocytes and Macrophages.单核细胞和巨噬细胞的表型与功能异质性
Int J Mol Sci. 2023 Sep 25;24(19):14525. doi: 10.3390/ijms241914525.
2
Generation and Functional Characterization of Monocytes and Macrophages Derived from Human Induced Pluripotent Stem Cells.人诱导多能干细胞来源的单核细胞和巨噬细胞的生成和功能特征。
Curr Protoc Stem Cell Biol. 2020 Mar;52(1):e108. doi: 10.1002/cpsc.108.
3
Cytokine repertoire during maturation of monocytes to macrophages within spheroids of malignant and non-malignant urothelial cell lines.恶性和非恶性尿路上皮细胞系球体中单核细胞向巨噬细胞成熟过程中的细胞因子谱。
Int J Cancer. 1998 Nov 23;78(5):648-53. doi: 10.1002/(sici)1097-0215(19981123)78:5<648::aid-ijc20>3.0.co;2-n.
4
Synergism between phorbol-12-myristate-13-acetate and vitamin D3 in the differentiation of U937 cells to monocytes and macrophages.佛波醇-12-肉豆蔻酸酯-13-乙酸酯与维生素D3在U937细胞向单核细胞和巨噬细胞分化过程中的协同作用。
Morphologie. 2018 Sep;102(338):205-218. doi: 10.1016/j.morpho.2018.06.001. Epub 2018 Jul 31.
5
Adenylate Cyclase Toxin Inhibits Monocyte-to-Macrophage Transition and Dedifferentiates Human Alveolar Macrophages into Monocyte-like Cells.腺苷酸环化酶毒素抑制单核细胞向巨噬细胞的转化，并将人肺泡巨噬细胞去分化为单核细胞样细胞。
mBio. 2019 Sep 24;10(5):e01743-19. doi: 10.1128/mBio.01743-19.
6
Isolation and Analysis of Human Monocytes and Adipose Tissue Macrophages.人单核细胞和脂肪组织巨噬细胞的分离与分析。
Methods Mol Biol. 2019;1951:33-48. doi: 10.1007/978-1-4939-9130-3_3.
7
Eltrombopag modulates the phenotypic evolution and potential immunomodulatory roles of monocytes/macrophages in immune thrombocytopenia.依洛尤单抗调节免疫性血小板减少症中单核细胞/巨噬细胞的表型演变和潜在免疫调节作用。
Platelets. 2023 Dec;34(1):2135694. doi: 10.1080/09537104.2022.2135694. Epub 2022 Oct 25.
8
Polycyclic aromatic hydrocarbons inhibit differentiation of human monocytes into macrophages.多环芳烃抑制人类单核细胞分化为巨噬细胞。
J Immunol. 2003 Mar 1;170(5):2374-81. doi: 10.4049/jimmunol.170.5.2374.
9
Rhizoctonia bataticola lectin (RBL) induces phenotypic and functional characteristics of macrophages in THP-1 cells and human monocytes.甘薯丝核菌凝集素（RBL）诱导THP-1细胞和人单核细胞中巨噬细胞的表型和功能特性。
Immunol Lett. 2015 Feb;163(2):163-72. doi: 10.1016/j.imlet.2014.12.005. Epub 2014 Dec 30.
10
Sulforaphane regulates phenotypic and functional switching of both induced and spontaneously differentiating human monocytes.萝卜硫素可调节诱导分化和自发分化的人类单核细胞的表型及功能转换。
Int Immunopharmacol. 2016 Jun;35:85-98. doi: 10.1016/j.intimp.2016.03.008. Epub 2016 Apr 16.

引用本文的文献

1
HIV-1 Myeloid Reservoirs - Contributors to Viral Persistence and Pathogenesis.HIV-1 髓系储库——病毒持续存在和发病机制的贡献者。
Curr HIV/AIDS Rep. 2024 Apr;21(2):62-74. doi: 10.1007/s11904-024-00692-2. Epub 2024 Feb 27.

本文引用的文献

1
Monocyte Differentiation and Heterogeneity: Inter-Subset and Interindividual Differences.单核细胞分化和异质性：亚群间和个体间差异。
Int J Mol Sci. 2023 May 15;24(10):8757. doi: 10.3390/ijms24108757.
2
An Eye on Kupffer Cells: Development, Phenotype and the Macrophage Niche.关注库普弗细胞：发育、表型和巨噬细胞龛。
Int J Mol Sci. 2022 Aug 30;23(17):9868. doi: 10.3390/ijms23179868.
3
Quantitative Analysis of the Transcriptome of Two Commonly Used Human Monocytic Cell Lines-THP-1 and Mono Mac 6-Reveals Their Arrest during Early Monocyte/Neutrophil Differentiation.
两种常用人单核细胞系（THP-1 和 Mono Mac 6）转录组的定量分析表明，它们在早期单核细胞/中性粒细胞分化过程中被阻滞。
Int J Mol Sci. 2022 May 22;23(10):5818. doi: 10.3390/ijms23105818.
4
The Human Monocyte-A Circulating Sensor of Infection and a Potent and Rapid Inducer of Inflammation.人类单核细胞——感染的循环传感器，也是一种强大而迅速的炎症诱导剂。
Int J Mol Sci. 2022 Mar 31;23(7):3890. doi: 10.3390/ijms23073890.
5
Quantitative In-Depth Transcriptome Analysis Implicates Peritoneal Macrophages as Important Players in the Complement and Coagulation Systems.定量深入转录组分析表明，腹膜巨噬细胞是补体和凝血系统的重要参与者。
Int J Mol Sci. 2022 Jan 21;23(3):1185. doi: 10.3390/ijms23031185.
6
CD116+ fetal precursors migrate to the perinatal lung and give rise to human alveolar macrophages.CD116+ 胎儿前体细胞迁移到围生期肺，并产生人类肺泡巨噬细胞。
J Exp Med. 2022 Feb 7;219(2). doi: 10.1084/jem.20210987. Epub 2022 Jan 12.
7
Network analysis of transcriptomic diversity amongst resident tissue macrophages and dendritic cells in the mouse mononuclear phagocyte system.在小鼠单核吞噬细胞系统中，驻留组织巨噬细胞和树突状细胞的转录组多样性的网络分析。
PLoS Biol. 2020 Oct 8;18(10):e3000859. doi: 10.1371/journal.pbio.3000859. eCollection 2020 Oct.
8
Cnidarian Immunity and the Repertoire of Defense Mechanisms in Anthozoans.刺胞动物的免疫及珊瑚虫纲动物的防御机制库
Biology (Basel). 2020 Sep 11;9(9):283. doi: 10.3390/biology9090283.
9
Determinants of Resident Tissue Macrophage Identity and Function.决定驻留组织巨噬细胞特性和功能的因素。
Immunity. 2020 Jun 16;52(6):957-970. doi: 10.1016/j.immuni.2020.05.014.
10
Developmental and Functional Heterogeneity of Monocytes.单核细胞的发育和功能异质性。
Immunity. 2018 Oct 16;49(4):595-613. doi: 10.1016/j.immuni.2018.10.005.