Department of Basic Sciences, Faculty of Health Sciences, Wrocław Medical University, Chałubińskiego 4, 50-368 Wroclaw, Poland.
Department of Microbiology, Faculty of Biological Sciences, University of Wrocław, Przybyszewskiego 63-77, 51-148 Wroclaw, Poland.
Int J Mol Sci. 2023 Sep 26;24(19):14579. doi: 10.3390/ijms241914579.
European Union (EU) countries strive to improve the quality and safety of food of animal origin. Food production depends on a good microbiological quality of fodder. However, feed can be a reservoir or vector of pathogenic microorganisms, including or bacteria. spp. and are the two most important food-borne pathogens of public health concern. Contamination with these pathogens, mainly in the poultry sector, can lead to serious food-borne diseases. Both microorganisms can form biofilms on abiotic and biotic surfaces. The cells that form biofilms are less sensitive to disinfectants, which in turn makes it difficult to eliminate them from various surfaces. Because the usage of formaldehyde in animal feed is prohibited in European countries, the replacement of this antibacterial with natural plant products seems very promising. This study aimed to assess the inhibitory effectiveness of extract against biofilm produced by model and strains. We found that formaldehyde could effectively kill both species of bacterial cells in biofilm, while the lingonberry extract showed some antibiofilm effect on serovar Senftenberg. In conclusion, finding natural plant products that are effective against biofilms formed by Gram-negative bacteria is still challenging.
欧盟国家努力提高动物源食品的质量和安全性。食品生产依赖于饲料良好的微生物质量。然而，饲料可能是病原微生物的储存库或载体，包括 或 细菌。 spp. 和 是公众健康关注的两种最重要的食源性病原体。这些病原体的污染，主要在禽类部门，可能导致严重的食源性疾病。这两种微生物都可以在非生物和生物表面形成生物膜。形成生物膜的细胞对消毒剂的敏感性较低，这反过来又使它们难以从各种表面消除。由于甲醛在欧洲国家的动物饲料中被禁止使用，用天然植物产品替代这种抗菌剂似乎很有前途。本研究旨在评估 提取物对模式 和 菌株生物膜的抑制效果。我们发现甲醛可以有效地杀死生物膜中的两种细菌细胞，而越桔提取物对 血清型森滕贝格表现出一定的抗生物膜作用。总之，寻找对革兰氏阴性菌形成的生物膜有效的天然植物产品仍然具有挑战性。
