Barrett G D, Constable I J, Stewart A D
J Cataract Refract Surg. 1986 Nov;12(6):623-31. doi: 10.1016/s0886-3350(86)80076-1.
Polymethylmethacrylate has proven to be a useful intraocular lens (IOL) implant material and remains the most widely used material for the fabrication of IOLs. Complications, however, from IOL implantation still occur. A hydrogel lens has been designed for posterior chamber placement. A clinical study from August 1983 to June 1985 was undertaken to determine the safety and efficacy of this new lens manufactured from 38% poly HEMA. The noninflammatory postoperative complications were limited to lens decentration and opacification of the lens capsule. Three cases of posterior capsule opacification required YAG laser capsulotomy. Laser capsulotomy is feasible and the lens appeared to be more resistant to damage from the YAG laser than polymethylmethacrylate lenses. In general, the material appeared to be well tolerated and there have been no cases of persistent iritis or clinically detectable cystoid macular edema. If the visual acuity outcome by age decade for all patients irrespective of follow-up time is considered, 92% of patients achieved 20/40 or better corrected visual acuity.
聚甲基丙烯酸甲酯已被证明是一种有用的人工晶状体(IOL)植入材料,并且仍然是制造人工晶状体最广泛使用的材料。然而,人工晶状体植入的并发症仍然会发生。一种水凝胶晶状体被设计用于后房植入。1983年8月至1985年6月进行了一项临床研究,以确定这种由38%聚甲基丙烯酸羟乙酯制成的新型晶状体的安全性和有效性。术后无炎症并发症仅限于晶状体偏位和晶状体囊膜混浊。三例后囊膜混浊需要进行YAG激光晶状体囊切开术。激光晶状体囊切开术是可行的,并且这种晶状体似乎比聚甲基丙烯酸甲酯晶状体更能抵抗YAG激光的损伤。总体而言,这种材料似乎耐受性良好,没有持续性虹膜炎或临床可检测到的黄斑囊样水肿病例。如果考虑所有患者无论随访时间的按年龄十年划分的视力结果,92%的患者矫正视力达到20/40或更好。