Hayashi K, Hayashi H
Hayashi Eye Hospital, 4-7-13 Hakataekimae, Hakata-Ku, Fukuoka 812, Japan.
Br J Ophthalmol. 2004 Feb;88(2):182-5. doi: 10.1136/bjo.2003.023580.
To compare the degree of posterior capsule opacification (PCO) in eyes with a hydrophilic hydrogel intraocular lens (IOL) with that in eyes with a hydrophobic acrylic IOL.
Ninety five patients underwent a hydrogel IOL implantation in one eye and an acrylic IOL implantation in the opposite eye. The PCO value of these patients was measured using the Scheimpflug videophotography system at 1, 6, 12, 18, and 24 months postoperatively. The rate of neodymium:YAG (Nd:YAG) laser posterior capsulotomy and visual acuity were also evaluated.
The mean PCO value in the hydrogel group increased significantly (p<0.0001), while that in the acrylic group did not show significant change. The PCO value in the hydrogel group was significantly greater than that in the acrylic group throughout the follow up period. Kaplan-Meier survival analysis determined that the Nd:YAG capsulotomy rate in the hydrogel group was significantly higher than that in the acrylic group (p<0.0001). Mean visual acuity in the hydrogel group decreased significantly with time (p<0.0001), and became significantly worse than that in the acrylic group at 18 and 24 months postoperatively.
Posterior capsule opacification in eyes with a hydrophilic hydrogel IOL is significantly more extensive than that in eyes with a hydrophobic acrylic IOL, and results in a significant impairment of visual acuity.
比较植入亲水性水凝胶人工晶状体（IOL）的眼与植入疏水性丙烯酸酯人工晶状体的眼的后囊膜混浊（PCO）程度。
95例患者一只眼植入水凝胶人工晶状体，另一只眼植入丙烯酸酯人工晶状体。术后1、6、12、18和24个月使用Scheimpflug摄像系统测量这些患者的PCO值。还评估了钕：钇铝石榴石（Nd：YAG）激光后囊切开术的发生率和视力。
水凝胶组的平均PCO值显著增加（p<0.0001），而丙烯酸酯组未显示出显著变化。在整个随访期间，水凝胶组的PCO值显著高于丙烯酸酯组。Kaplan-Meier生存分析确定水凝胶组的Nd：YAG囊切开术发生率显著高于丙烯酸酯组（p<0.0001）。水凝胶组的平均视力随时间显著下降（p<0.0001），并在术后18和24个月时显著低于丙烯酸酯组。
植入亲水性水凝胶人工晶状体的眼的后囊膜混浊比植入疏水性丙烯酸酯人工晶状体的眼明显更广泛，并导致视力显著受损。
