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炎症性肠病的手术指征及手术结果

Indications for and results of operation in inflammatory bowel disease.

作者信息

Schofield P F, Manson J M

出版信息

J R Soc Med. 1986 Oct;79(10):593-5. doi: 10.1177/014107688607901012.

Abstract

Of 363 patients with inflammatory bowel disease presenting between 1972 and 1983, 166 required definitive operation. A classification by histological type distinguishes Crohn's disease (CD) from ulcerative colitis (UC) and indeterminate inflammatory bowel disease. CD is divided into predominantly ileal disease (81), total or subtotal colonic disease (74) and distal disease (22), whilst UC is classified into colonic (95) or distal disease (63). Most patients with ileal disease required operation for chronic persistent symptoms. In patients with total colonic involvement a greater proportion of patients with CD than those with UC came to surgery. Very few patients with distal disease required surgery. After resection for ileal disease there was a low incidence of anastomotic leakage (3%) and no operative mortality. There was an overall operative mortality of 8% after colonic resection. This was much lower in the non-urgent cases but rose to 12% in urgent cases.

摘要

在1972年至1983年间就诊的363例炎症性肠病患者中,166例需要进行确定性手术。根据组织学类型分类可将克罗恩病(CD)与溃疡性结肠炎(UC)以及不确定型炎症性肠病区分开来。CD分为主要累及回肠的疾病(81例)、全结肠或次全结肠疾病(74例)以及远端疾病(22例),而UC则分为结肠疾病(95例)或远端疾病(63例)。大多数回肠疾病患者因慢性持续症状而需要手术。在全结肠受累的患者中,CD患者接受手术的比例高于UC患者。极少有远端疾病患者需要手术。回肠疾病切除术后吻合口漏的发生率较低(3%),且无手术死亡病例。结肠切除术后的总体手术死亡率为8%。在非紧急病例中这一比例要低得多,但在紧急病例中则升至12%。

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