Ligarda-Samanez Carlos A, Moscoso-Moscoso Elibet, Choque-Quispe David, Ramos-Pacheco Betsy S, Arévalo-Quijano José C, Cruz Germán De la, Huamán-Carrión Mary L, Quispe-Quezada Uriel R, Gutiérrez-Gómez Edgar, Cabel-Moscoso Domingo J, Muñoz-Melgarejo Mauricio, Calsina Ponce Wilber César
Nutraceuticals and Biomaterials Research Group, Universidad Nacional José María Arguedas, Andahuaylas 03701, Peru.
Research Group in the Development of Advanced Materials for Water and Food Treatment, Universidad Nacional José María Arguedas, Andahuaylas 03701, Peru.
Polymers (Basel). 2023 Oct 4;15(19):3985. doi: 10.3390/polym15193985.
Iron deficiency leads to ferropenic anemia in humans. This study aimed to encapsulate iron-rich ovine and bovine erythrocytes using tara gum and native potato starch as matrices. Solutions containing 20% erythrocytes and different proportions of encapsulants (5, 10, and 20%) were used, followed by spray drying at 120 and 140 °C. Iron content in erythrocytes ranged between 2.24 and 2.52 mg of Fe/g; microcapsules ranged from 1.54 to 2.02 mg of Fe/g. Yields varied from 50.55 to 63.40%, and temperature and encapsulant proportion affected moisture and water activity. Various red hues, sizes, and shapes were observed in the microcapsules. SEM-EDS analysis revealed the surface presence of iron in microcapsules with openings on their exterior, along with a negative zeta potential. Thermal and infrared analyses confirmed core encapsulation within the matrices. Iron release varied between 92.30 and 93.13% at 120 min. Finally, the most effective treatments were those with higher encapsulant percentages and dried at elevated temperatures, which could enable their utilization in functional food fortification to combat anemia in developing countries.
缺铁会导致人类患缺铁性贫血。本研究旨在以塔拉胶和天然马铃薯淀粉为基质，对富含铁的绵羊和牛红细胞进行包封。使用含有20%红细胞和不同比例包封剂（5%、10%和20%）的溶液，然后在120℃和140℃下进行喷雾干燥。红细胞中的铁含量在2.24至2.52毫克铁/克之间；微胶囊中的铁含量在1.54至2.02毫克铁/克之间。产率在50.55%至63.40%之间，温度和包封剂比例会影响水分和水分活度。在微胶囊中观察到了各种红色色调、大小和形状。扫描电子显微镜-能谱分析表明，微胶囊表面存在铁，其外部有开口，同时具有负的zeta电位。热分析和红外分析证实了基质内的核心包封。在120分钟时，铁释放率在92.30%至93.13%之间。最后，最有效的处理方法是使用较高包封剂百分比并在高温下干燥的方法，这可以使其用于功能性食品强化，以对抗发展中国家的贫血症。
