Vagaiwala M R, Robinson J S, Galicich J H, Gralla R J, Helson L, Beattie E J
Cancer. 1979 Jul;44(1):326-33. doi: 10.1002/1097-0142(197907)44:1<326::aid-cncr2820440156>3.0.co;2-4.
A case is discussed in which the patient presented with a primary extradural sacrococcygeal ependymoma and synchronous pulmonary metastasis. The clinical course has been characterized by recurrent pulmonary metastases. Management has consisted of repeated surgical resections of the pulmonary metastases and the tumor at the primary site; and the use of a wide spectrum of chemotherapeutic agents. Transplantation of this tumor into nude mice initially resulted in rapid growth but there was spontaneous regression in the second transplants. A general discussion of the management of such lesions is presented, and the literature pertaining to this tumor is discussed.
本文讨论了一例患者，其表现为原发性硬膜外骶尾部室管膜瘤并伴有同步肺转移。临床病程的特点是肺转移反复出现。治疗包括对肺转移灶和原发部位肿瘤进行反复手术切除，以及使用多种化疗药物。将该肿瘤移植到裸鼠体内，最初导致肿瘤快速生长，但第二次移植时出现了自发消退。本文对这类病变的治疗进行了一般性讨论，并探讨了与该肿瘤相关的文献。
