Key Laboratory of Trace Element Nutrition of National Health Commission (NHC), National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Beijing Chaoyang District Center for Disease Control and Prevention, Beijing 100050, China.
Nutrients. 2023 Sep 27;15(19):4185. doi: 10.3390/nu15194185.
This study aimed to develop a predictive equation for basal metabolic rate (BMR) in normal-weight Chinese adults and provide a reference for establishing the national recommended dietary energy intake. A new equation for BMR was derived from a sample of 516 normal-weight Chinese adults (men = 253, women = 263), and this sample was collected from two previous studies. Furthermore, the accuracy of this new equation and eight other previous predictive equations was reviewed. The agreement and reliability were compared in terms of bias, accuracy, the intraclass correlation coefficient, and Bland-Altman plots between predictive equations. In addition, the newly developed equation was further verified using a small independent sample, which contained 41 healthy Chinese adults (men = 21, women = 20). The measured BMR (mBMR) of all participants, measured using indirect calorimetry, was 1346.2 ± 358.0 kcal/d. Thirty participants were excluded based on Cook's distance criteria (Cook's distance of ≥0.008). Previous equations developed by Henry, Schofield, Harris-Benedict (H-B), Yang, and Hong overestimated the BMR of healthy Chinese adults. The present equation displayed the smallest average bias (0.2 kcal/d) between the mBMR and predicted basal metabolic rate (pBMR). The limits of agreement of the present equation from Bland-Altman plots were -514.3 kcal/d and 513.9 kcal/d, which is the most narrow and balanced limit of agreement. Moreover, in the verification of the testing database, the pBMR of the new equation was not significantly different from the mBMR, and the accuracy was 75.6%. Compared with pre-existing equations, the present equation is more applicable to the prediction of BMR in healthy Chinese adults. However, further studies are required to verify the accuracy of this new equation.
本研究旨在为中国正常体重成年人制定基础代谢率(BMR)的预测方程,为制定国家推荐膳食能量摄入量提供参考。从之前两项研究中抽取的 516 名正常体重中国成年人(男性=253 人,女性=263 人)样本中得出了新的 BMR 方程。此外,还评估了新方程和其他 8 个预测方程的准确性。从偏差、准确性、组内相关系数和 Bland-Altman 图方面比较了预测方程的一致性和可靠性。此外,还使用包含 41 名健康中国成年人(男性=21 人,女性=20 人)的小独立样本进一步验证了新开发的方程。所有参与者的基础代谢率(mBMR)均使用间接热量法测量,结果为 1346.2±358.0kcal/d。根据 Cook 距离标准(Cook 距离≥0.008)排除了 30 名参与者。Henry、Schofield、Harris-Benedict(H-B)、Yang 和 Hong 之前开发的方程高估了健康中国成年人的 BMR。本研究提出的方程在 mBMR 和预测基础代谢率(pBMR)之间的平均偏差最小(0.2kcal/d)。Bland-Altman 图的本方程的一致性界限为-514.3kcal/d 和 513.9kcal/d,这是最窄和平衡的一致性界限。此外,在测试数据库的验证中,新方程的 pBMR 与 mBMR 无显著差异,准确率为 75.6%。与现有的方程相比,本研究提出的方程更适用于预测中国健康成年人的 BMR。然而,还需要进一步的研究来验证这个新方程的准确性。