Research Center for Environmental Pollutants, Department of Environmental Health Engineering, Faculty of Health, Qom University of Medical Sciences, Qom, Iran.
Department of Epidemiology and Biostatistics, Faculty of Health, Qom University of Medical Sciences, Qom, Iran.
Environ Res. 2023 Dec 15;239(Pt 2):117392. doi: 10.1016/j.envres.2023.117392. Epub 2023 Oct 12.
Recent studies have indicated that air pollution (AP) has harmful effects on hearing and ear diseases such as Sudden Sensorineural Hearing Loss (SSHL). The purpose of this study was to evaluate the impact of exposure to AP on SSHL incidence. Valid electronic databases were searched to retrieve studies published until December 1, 2022, using appropriate keywords. The result of the search was 1146 studies, and after screening according to the defined criteria, in total 8 studies were obtained. The risk of bias (ROB) in the studies and their quality were assessed. Finally, the meta-analysis with a significance level of 5% was performed. The findings revealed that the mean level of SO, CO, NO, and PM in the patient group was more than that of the control group, and p-values were 0.879, 0.144, 0.077, and 0.138, respectively. There was an indirect relation between air pollutants and SSHL, and PM showed a significant effect (p < 0.05). Given the limited research and the use of different statistical methods, more research is suggested to confirm this association and to determine the mechanisms by which AP exposure may cause SSHL.
最近的研究表明，空气污染（AP）对听力和耳部疾病有不良影响，如突发性聋（SSHL）。本研究旨在评估暴露于 AP 对 SSHL 发病率的影响。检索了截至 2022 年 12 月 1 日发表的有效电子数据库，使用了适当的关键字。搜索结果为 1146 项研究，根据定义的标准进行筛选后，共获得 8 项研究。评估了研究中的偏倚风险（ROB）及其质量。最后，进行了具有 5%显著性水平的荟萃分析。研究结果表明，患者组的 SO、CO、NO 和 PM 的平均水平高于对照组，p 值分别为 0.879、0.144、0.077 和 0.138。空气污染物与 SSHL 之间存在间接关系，PM 表现出显著影响（p<0.05）。鉴于研究有限且使用了不同的统计方法，建议进行更多的研究来证实这种关联，并确定 AP 暴露可能导致 SSHL 的机制。
