Affiliated Hospital of Nantong University, Nantong, Jiangsu, China.
Changshu No 2 People's Hospital, Changshu, Jiangsu, China
BMJ Open. 2024 Sep 28;14(9):e085884. doi: 10.1136/bmjopen-2024-085884.
To explore the associations of air pollutants and Air Quality Index (AQI) with risk of sudden sensorineural hearing loss (SSNHL) DESIGN: Cross-sectional study SETTING: Medical record data and local population data collected between 2014 and 2022 in Changshu, China were retrospectively reviewed.
Adults aged 18 years and above who were diagnosed with SSNHL in Changshu No. 1 People's Hospital or Changshu No. 2 People's Hospital from the spring of 2014 to the fall of 2022 were included in the study.
SSNHL was diagnosed by clinicians using the Chinese diagnostic criteria for SSNHL.
Compared with those exposed to the lowest tertile of carbon monoxide (CO), the prevalence ratio for those exposed to middle and high tertiles of CO were 1.113 (95% CI 1.022 to 1.213) and 1.230 (95% CI 1.105 to 1.369), respectively. The risk of SSNHL was increased by 30.6% (95% CI 9.9% to 55.4%) per doubling increment of CO. No categorical association was found between ozone (O) exposure and risk of SSNHL, however, an increased risk of 22.2% (0.8%-48.2%) was identified for each doubling of O. No association was identified between other pollutants and AQI and risk of SSNHL.
In this study, CO and O were associated with an increased risk of SSNHL in Changshu, China. Further studies are warranted to confirm our findings.
探讨空气污染物和空气质量指数（AQI）与突发性聋（SSNHL）风险之间的关系。
回顾性队列研究。
在中国常熟，回顾性分析了 2014 年至 2022 年间收集的医疗记录数据和当地人口数据。
2014 年春季至 2022 年秋季在常熟市第一人民医院或常熟市第二人民医院被诊断为 SSNHL 的 18 岁及以上成年人。
SSNHL 由临床医生根据中国 SSNHL 诊断标准进行诊断。
与暴露于一氧化碳（CO）最低三分位的患者相比，暴露于 CO 中、高分位的患者 SSNHL 的患病率比分别为 1.113（95%CI：1.022-1.213）和 1.230（95%CI：1.105-1.369）。CO 每增加一倍，SSNHL 的风险增加 30.6%（95%CI：9.9%-55.4%）。臭氧（O）暴露与 SSNHL 风险之间无分类关联，但 O 每增加一倍，SSNHL 的风险增加 22.2%（0.8%-48.2%）。未发现其他污染物与 AQI 与 SSNHL 风险之间存在关联。
在本研究中，CO 和 O 与中国常熟的 SSNHL 风险增加有关。需要进一步的研究来证实我们的发现。
