Blanchard P D, Yao J D, McAlpine D E, Hurt R D
JAMA. 1986 Dec 12;256(22):3131-3.
Eight cases of suicidal isoniazid overdose by Cambodian refugees are reviewed. In all patients generalized seizures and metabolic acidosis developed. Treatment included supportive measures and intravenous pyridoxine hydrochloride. There were no deaths. Psychiatric evaluation of each patient revealed usual and extraordinary life and social adjustment stresses. Indochinese immigrants are a subpopulation at risk for isoniazid overdose.
对8例柬埔寨难民自杀性过量服用异烟肼的病例进行了回顾。所有患者均出现全身性癫痫发作和代谢性酸中毒。治疗措施包括支持性治疗及静脉注射盐酸吡哆醇。无死亡病例。对每位患者的精神科评估显示，他们均面临着常见及特殊的生活和社会适应压力。印度支那移民是异烟肼过量服用的高危亚人群。
