Universidade Católica Portuguesa, CBQF-Centro de Biotecnologia e Química Fina-Laboratório Associado, Escola Superior de Biotecnologia, Rua Diogo Botelho 1327, 4169-005 Porto, Portugal.
Universidade Católica Portuguesa, CBQF-Centro de Biotecnologia e Química Fina-Laboratório Associado, Escola Superior de Biotecnologia, Rua Diogo Botelho 1327, 4169-005 Porto, Portugal; Amyris Bio Products Portugal, Unipessoal Lda, Rua Diogo Botelho 1327, 4169-005 Porto, Portugal.
Carbohydr Polym. 2023 Dec 15;322:121329. doi: 10.1016/j.carbpol.2023.121329. Epub 2023 Aug 23.
β-Glucans, which are naturally present in cereals, yeast, and mushrooms, have gained attention as a potential natural source for functional foods and pharmaceuticals. Due to the availability of β-glucans from several sources, different extraction methods can be employed to obtain high purity extracts that can be further modified to enhance their solubility or other biological properties. Apart from their known ability to interact with the immune system, β-glucans possess specific properties that could benefit overall skin health and prevent age-related signs, including soothing and antioxidant activities. As a result, the use of β-glucans to mitigate damage caused by environmental stressors or skin-related issues that accelerate skin aging or trigger chronic inflammation may represent a promising, natural, eco-friendly, and cost-effective approach to maintaining skin homeostasis balance. This review outlines β-glucan extraction methodologies, molecular structure, functionalization approaches, and explores skin-related benefits of β-glucans, along with an overview of related products in the market.
β-葡聚糖天然存在于谷物、酵母和蘑菇中，作为功能性食品和药物的潜在天然来源备受关注。由于可以从多种来源获得β-葡聚糖，因此可以采用不同的提取方法来获得高纯度的提取物，然后进一步修饰以提高其溶解度或其他生物学特性。除了已知的与免疫系统相互作用的能力外，β-葡聚糖还具有一些特殊的特性，可以有益于整体皮肤健康并预防与年龄相关的迹象，包括舒缓和抗氧化活性。因此，使用β-葡聚糖来减轻环境胁迫或加速皮肤衰老或引发慢性炎症的皮肤相关问题造成的损害，可能是维持皮肤内稳态平衡的一种很有前景、天然、环保且具有成本效益的方法。本文综述了β-葡聚糖的提取方法、分子结构、功能化方法，并探讨了β-葡聚糖的皮肤相关益处，以及市场上相关产品的概述。
