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探索β-葡聚糖在皮肤护理中的特性及应用潜力。

Exploring the Properties and Application Potential of β-Glucan in Skin Care.

作者信息

Feng Xiaoyue, Shang Jianli, Wang Yuhui, Chen Yong, Liu Youting

机构信息

R&D Department Beijing UPROVEN Medical Technology co., Ltd. Beijing China.

Beijing UPROVEN Institute of Dermatology Beijing China.

出版信息

Food Sci Nutr. 2025 Apr 25;13(4):e70212. doi: 10.1002/fsn3.70212. eCollection 2025 Apr.

DOI:10.1002/fsn3.70212
PMID:40291929
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12023766/
Abstract

β-glucan is a natural polysaccharide widely found in plants, fungi, bacteria, and algae. Due to its significant immunomodulatory effects, it has become an important source for functional foods and pharmaceuticals. In addition to immune regulation, β-glucan also exhibits various bioactivities, including antioxidant, anti-inflammatory, barrier repair, and moisturizing effects, demonstrating great potential for applications in skin care. Its biological activity is influenced by factors such as its source, molecular structure, and physicochemical properties. This review systematically explores the relationship between the properties and functions of β- glucan, investigates its biological mechanisms, and summarizes its clinical applications and future prospects in skin care. The aim of this paper is to provide theoretical support for the development of β-glucan in the field of skin health and offer references for future related research and clinical practice.

摘要

β-葡聚糖是一种广泛存在于植物、真菌、细菌和藻类中的天然多糖。由于其显著的免疫调节作用,它已成为功能性食品和药物的重要来源。除了免疫调节外,β-葡聚糖还具有多种生物活性,包括抗氧化、抗炎、屏障修复和保湿作用,在皮肤护理方面显示出巨大的应用潜力。其生物活性受其来源、分子结构和理化性质等因素影响。本文系统地探讨了β-葡聚糖的性质与功能之间的关系,研究了其生物学机制,并总结了其在皮肤护理中的临床应用和未来前景。本文旨在为β-葡聚糖在皮肤健康领域的开发提供理论支持,并为未来相关研究和临床实践提供参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2426/12023766/1451a4345511/FSN3-13-e70212-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2426/12023766/6c2bd44c5dcd/FSN3-13-e70212-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2426/12023766/0187ab7cf75a/FSN3-13-e70212-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2426/12023766/875439f3f7b6/FSN3-13-e70212-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2426/12023766/1451a4345511/FSN3-13-e70212-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2426/12023766/6c2bd44c5dcd/FSN3-13-e70212-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2426/12023766/0187ab7cf75a/FSN3-13-e70212-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2426/12023766/875439f3f7b6/FSN3-13-e70212-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2426/12023766/1451a4345511/FSN3-13-e70212-g001.jpg

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本文引用的文献

1
Anti-Photodamage Effect of Murill Polysaccharide on UVB-Damaged HaCaT Cells.Murill 多糖对 UVB 损伤的 HaCaT 细胞的光保护作用。
Int J Mol Sci. 2024 Apr 25;25(9):4676. doi: 10.3390/ijms25094676.
2
Oat β-glucan repairs the epidermal barrier by upregulating the levels of epidermal differentiation, cell-cell junctions and lipids via Dectin-1.燕麦β-葡聚糖通过Dectin-1上调表皮分化、细胞间连接和脂质水平来修复表皮屏障。
Br J Pharmacol. 2024 Jun;181(11):1596-1613. doi: 10.1111/bph.16306. Epub 2024 Jan 28.
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β-Glucan extracts as high-value multifunctional ingredients for skin health: A review.
β-葡聚糖提取物作为高附加值多功能的皮肤健康成分:综述。
Carbohydr Polym. 2023 Dec 15;322:121329. doi: 10.1016/j.carbpol.2023.121329. Epub 2023 Aug 23.
4
Exploring β-glucan as a micro-nano system for oral delivery targeted the colon.探索β-葡聚糖作为一种靶向结肠的口服给药的微纳米系统。
Int J Biol Macromol. 2023 Dec 31;253(Pt 6):127360. doi: 10.1016/j.ijbiomac.2023.127360. Epub 2023 Oct 10.
5
β-glucan-induced disease resistance in plants: A review.β-葡聚糖诱导植物抗病性:综述。
Int J Biol Macromol. 2023 Dec 31;253(Pt 4):127043. doi: 10.1016/j.ijbiomac.2023.127043. Epub 2023 Sep 22.
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Update on Atopic Dermatitis.特应性皮炎更新。
Adv Pediatr. 2023 Aug;70(1):157-170. doi: 10.1016/j.yapd.2023.03.006. Epub 2023 May 5.
7
Immunomodulatory Effect and Biological Significance of β-Glucans.β-葡聚糖的免疫调节作用及生物学意义
Pharmaceutics. 2023 May 29;15(6):1615. doi: 10.3390/pharmaceutics15061615.
8
Chemical modifications in the structure of marine polysaccharide as serviceable food processing and preservation assistant: A review.海洋多糖结构中的化学修饰作为实用的食品加工和保鲜助剂:综述
Int J Biol Macromol. 2022 Dec 31;223(Pt A):1539-1555. doi: 10.1016/j.ijbiomac.2022.11.034. Epub 2022 Nov 10.
9
Mushroom β-Glucan Recovered from Antler-Type Fruiting Body of by Enzymatic Process and Its Potential Biological Activities for Cosmeceutical Applications.通过酶法从鹿茸型子实体中提取的蘑菇β-葡聚糖及其在药妆应用中的潜在生物活性。
Polymers (Basel). 2022 Oct 7;14(19):4202. doi: 10.3390/polym14194202.
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