Bissenbakker Kristine Henderson, Møller Anne, Jønsson Alexandra Brandt Ryborg, Brodersen John Brandt
Research Unit for General Practice and Section of General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
The Research Unit for General Practice in Region Zealand, Primary and eHealth Care, Region Zealand, Denmark.
Patient Relat Outcome Meas. 2023 Oct 10;14:269-282. doi: 10.2147/PROM.S427183. eCollection 2023.
To describe the processes of developing domains and items for the MultiMorbidity Questionnaire (MMQ), a multimorbidity-specific PROM for the assessment of Needs-based QoL.
We developed items and domains for the MMQ through 17 qualitative content validity questionnaire interviews with adults with multimorbidity by testing items from an item bank (covering items with content inspired by existing Needs-based QoL measures for single diseases). The interviews alternated between an explorative part and more focused cognitive interview techniques.
Testing the 47 items from the first draft of the MMQ items showed that the Needs-based approach as a framework did not cover all the QoL aspects our informants stated as being important. Therefore, the conceptual framework was supplemented by Self-perceived health inequity, and new items were generated. MMQ, measuring Needs-based QoL (MMQ1) and Self-perceived health inequity (MMQ2), was assembled. MMQ1 covers the domains: "Physical ability" (10 items), "Limitations in everyday life" (15 items), "Worries" (11 items), "My social life" (11 items), "Self-image" (12 items), and "Personal finances" (2 items). Self-perceived health inequity proved to be a relevant framework for other aspects of QoL not covered by the Needs-based approach to QoL. MMQ2 covers the domains: "Experiences of being stigmatized" (five items), "Experiences of not being seen and heard" (four items), "Insufficient understanding of the burden of disease" (three items) and "Experiences of feeling powerless" (five items).
We have developed the final MMQ draft, a multimorbidity-specific PROM for the assessment of Needs-based QoL (MMQ1) and Self-perceived health inequity (MMQ2) with high content validity (regarding content relevance and comprehensiveness). The final MMQ draft will be assessed for its psychometric properties using Modern Test Theory.
描述多病症问卷（MMQ）的领域和条目开发过程，MMQ是一种用于评估基于需求的生活质量的特定多病症患者报告结局量表。
我们通过对患有多种病症的成年人进行17次定性内容效度问卷调查访谈来开发MMQ的条目和领域，这些访谈通过测试条目库中的条目（涵盖受现有单一疾病基于需求的生活质量测量方法启发的内容的条目）进行。访谈在探索性部分和更具针对性的认知访谈技术之间交替进行。
对MMQ条目的初稿中的47个条目进行测试表明，基于需求的方法作为一个框架并未涵盖我们的受访者认为重要的所有生活质量方面。因此，概念框架通过自我感知的健康不平等进行了补充，并生成了新的条目。组装了测量基于需求的生活质量（MMQ1）和自我感知的健康不平等（MMQ2）的MMQ。MMQ1涵盖以下领域：“身体能力”（10个条目）、“日常生活中的限制”（15个条目）、“担忧”（11个条目）、“我的社交生活”（11个条目）、“自我形象”（12个条目）和“个人财务”（2个条目）。自我感知的健康不平等被证明是基于需求的生活质量方法未涵盖的生活质量其他方面的一个相关框架。MMQ2涵盖以下领域：“被污名化的经历”（5个条目）、“未被关注和倾听的经历”（4个条目）、“对疾病负担的理解不足”（3个条目）和“感到无力的经历”（5个条目）。
我们已经制定了最终的MMQ草案，这是一种用于评估基于需求的生活质量（MMQ1）和自我感知的健康不平等（MMQ2）的特定多病症患者报告结局量表，具有较高的内容效度（在内容相关性和全面性方面）。最终的MMQ草案将使用现代测试理论对其心理测量特性进行评估。
