Zhang Lindsay, Vogt Keith
Department of Anesthesiology and Perioperative Medicine, University of Pittsburgh School of Medicine, A-1305 Scaife Hall, 3550 Terrace Street, Pittsburgh, PA 15261, USA.
Data Brief. 2023 Oct 1;51:109634. doi: 10.1016/j.dib.2023.109634. eCollection 2023 Dec.
This is a report of unpublished data obtained from a randomized, single-blind, within-subject crossover design, neuroimaging trial comparing the effects of midazolam and ketamine on memory and pain. An experimental auditory paradigm paired with the periodic pain was used to examine auditory encoding and subsequent recognition. Psychometric surveys assessed stress, anxiety, depression, and pain behaviors. These data were collected to potentially characterize inter-subject variation during analysis. Electrodermal activity was measured to examine the association between previous pain-pairing of experimental items and autonomic responses during next day recognition memory testing, with exposure to the same auditory word items. Electrodermal responses were determined using an event-related analysis approach. These data may help shape future experiments using psychometric data to characterize individual responses or using next day electrodermal activity to determine conditioned responses to previously-experienced aversive stimuli.
这是一份关于未发表数据的报告，这些数据来自一项随机、单盲、受试者内交叉设计的神经影像学试验，该试验比较了咪达唑仑和氯胺酮对记忆和疼痛的影响。采用与周期性疼痛配对的实验性听觉范式来检查听觉编码和随后的识别。心理测量调查评估了压力、焦虑、抑郁和疼痛行为。收集这些数据是为了在分析过程中潜在地表征受试者间的差异。测量皮肤电活动，以检查实验项目先前的疼痛配对与第二天识别记忆测试期间自主反应之间的关联，测试中会接触相同的听觉单词项目。使用事件相关分析方法确定皮肤电反应。这些数据可能有助于规划未来的实验，即利用心理测量数据来表征个体反应，或利用第二天的皮肤电活动来确定对先前经历的厌恶刺激的条件反应。
