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用于减轻7至10岁儿童下牙槽神经阻滞时注射疼痛的蔗糖溶液:一项随机临床试验。

Sucrose solution for alleviating needle pain during inferior alveolar nerve block in children aged 7-10 years: a randomized clinical trial.

作者信息

Thambireddy Supriya, Svsg Nirmala, Nuvvula Sivakumar

机构信息

Department of Pediatric and Preventive Dentistry, Narayana Dental College and Hospital, Nellore, India.

出版信息

J Dent Anesth Pain Med. 2023 Oct;23(5):273-280. doi: 10.17245/jdapm.2023.23.5.273. Epub 2023 Sep 27.

Abstract

BACKGROUND

Intraoral local anesthesia is essential for delivering dental care; however, injection of this local anesthetic is perceived as the most painful and distressing agent for children, parents, and healthcare providers. Reducing pain as much as possible is essential to ensure smooth subsequent treatment procedures, especially in pediatric dentistry. In clinical practice, oral sucrose administration has been reported to decrease the pain during heel lance and cold pressor tests in neonates and children. This study aimed to determine whether the prior administration of a 30% sucrose solution reduced the pain related to inferior alveolar nerve block in children.

METHODS

A total of 42 healthy children aged 7-10 years requiring dental treatment of mandibular molars involving inferior alveolar nerve block were recruited. The participants' demographic details were recorded, height and weight were measured, and the anesthetic injection was delivered after receiving the respective intraoral sucrose solution and distilled water by the intervention (group 1) and control (group 2) group participants for 2 min. The subjective pain perceived during injection was measured using an animated emoji scale. The pain scores between the groups were compared using the Mann-Whitney U test.

RESULTS

The median pain score and range for the intervention and control groups were 4 (2 - 6) and 6 (4 - 8), respectively, and statistically significant differences (P < 0.001) were observed in the intervention group. Age, sex, height, and weight did not influence the analgesic effect of the sucrose solution.

CONCLUSION

Oral administration of sucrose may relieve pain associated with inferior alveolar nerve block in children.

摘要

背景

口腔局部麻醉是提供牙科护理所必需的;然而,这种局部麻醉剂的注射被认为是儿童、家长和医护人员最痛苦和令人苦恼的环节。尽可能减轻疼痛对于确保后续治疗程序顺利进行至关重要,尤其是在儿童牙科领域。在临床实践中,据报道口服蔗糖可减轻新生儿和儿童足跟采血及冷加压试验时的疼痛。本研究旨在确定预先给予30%蔗糖溶液是否能减轻儿童下牙槽神经阻滞相关的疼痛。

方法

共招募了42名年龄在7至10岁、需要对下颌磨牙进行涉及下牙槽神经阻滞的牙科治疗的健康儿童。记录参与者的人口统计学详细信息,测量身高和体重,干预组(1组)和对照组(2组)的参与者分别接受口腔蔗糖溶液和蒸馏水2分钟后进行麻醉注射。使用动画表情符号量表测量注射过程中感受到的主观疼痛。采用曼-惠特尼U检验比较两组之间的疼痛评分。

结果

干预组和对照组的中位疼痛评分及范围分别为4(2 - 6)和6(4 - 8),干预组观察到具有统计学意义的差异(P < 0.001)。年龄、性别、身高和体重均未影响蔗糖溶液的镇痛效果。

结论

口服蔗糖可能减轻儿童下牙槽神经阻滞相关的疼痛。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecdb/10567544/96b145ed4b62/jdapm-23-273-g001.jpg

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