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评估蔗糖与木糖醇用于减轻 5-7 岁儿童牙科注射疼痛的效果 - 一项随机对照初步研究。

Evaluation of the effectiveness of sucrose versus xylitol application in minimizing pain related to dental injection in 5-7-year-old children - A randomized controlled pilot study.

机构信息

Department of Pediatric and Preventive Dentistry, D.Y.Patil University, School of Dentistry, Navi Mumbai, Maharashtra, India.

Department of Oral Medicine and Radiology, D.Y.Patil University, School of Dentistry, Navi Mumbai, Maharashtra, India.

出版信息

J Indian Soc Pedod Prev Dent. 2023 Jul-Sep;41(3):216-221. doi: 10.4103/jisppd.jisppd_250_23.

DOI:10.4103/jisppd.jisppd_250_23
PMID:37861635
Abstract

BACKGROUND

Oral application of sweet-tasting solutions has found to be effective in minimizing pain on dental injection in children. Xylitol has never been tested in this regard.

AIM

The aim of this study was to compare the effectiveness of prior application of sucrose versus xylitol solution in minimizing pain on dental injection in 5-7-year-old children.

SETTINGS AND DESIGN

This study was a randomized controlled clinical trial.

MATERIALS AND METHODS

Informed consent was taken. A total of 30 children who required maxillary buccal infiltration injection were selected. The children were randomly allocated into the sucrose group, xylitol group, or control group by lottery method. In the sucrose and xylitol groups, 30% sucrose or 30% xylitol solution was applied on the lateral surface of the tongue for 2 min. In the control group, distilled water was applied. In all the groups, the topical anesthetic was applied at the site of injection followed by buccal infiltration. A video was taken during injection, and the sound eye-motor (SEM) scale was recorded by a blinded examiner. Patients were asked to self-evaluate using the Wong-Baker Faces Pain Scale (WBFPS).

STATISTICAL ANALYSIS

Mann-Whitney test was used to analyze the data.

RESULTS

There was a statistically significant difference in the WBFPS and the SEM score between the sucrose and the control group (P < 0.05) and the xylitol and control group (P < 0.05). No statistically significant difference was found between the sucrose and xylitol group.

CONCLUSION

The application of xylitol solution before dental injection was as effective as sucrose solution in minimizing pain during the injection.

摘要

背景

口服甜味溶液已被证明可有效减轻儿童牙科注射时的疼痛。木糖醇在此方面从未经过测试。

目的

本研究旨在比较在 5-7 岁儿童中,预先应用蔗糖与木糖醇溶液对减轻牙科注射疼痛的效果。

设置和设计

这是一项随机对照临床试验。

材料和方法

征得知情同意后,选择了 30 名需要上颌颊部浸润注射的儿童。通过抽签法将儿童随机分配到蔗糖组、木糖醇组或对照组。在蔗糖组和木糖醇组中,将 30%蔗糖或 30%木糖醇溶液涂于舌侧表面 2 分钟。在对照组中,应用蒸馏水。在所有组中,在注射部位应用局部麻醉剂后进行颊部浸润。在注射过程中拍摄视频,并由一名盲法检查者记录声音眼动(SEM)评分。患者使用 Wong-Baker 面部疼痛评分量表(WBFPS)进行自我评估。

统计分析

使用 Mann-Whitney 检验分析数据。

结果

蔗糖组和对照组(P < 0.05)以及木糖醇组和对照组(P < 0.05)之间的 WBFPS 和 SEM 评分存在统计学差异。但蔗糖组和木糖醇组之间无统计学差异。

结论

在牙科注射前应用木糖醇溶液与蔗糖溶液一样可有效减轻注射过程中的疼痛。

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引用本文的文献

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The efficacy of sweet solutions on dental injection related pain: a systematic review of randomized controlled trials.甜味溶液对牙科注射相关疼痛的疗效:随机对照试验的系统评价
J Dent Anesth Pain Med. 2025 Apr;25(2):83-96. doi: 10.17245/jdapm.2025.25.2.83. Epub 2025 Mar 27.
2
Efficacy of sucrose application in minimizing pain perception related to dental injection in children aged 3 to 9 years: a randomized control trial.蔗糖用于减轻3至9岁儿童牙科注射相关疼痛感知的疗效:一项随机对照试验。
J Dent Anesth Pain Med. 2024 Apr;24(2):109-117. doi: 10.17245/jdapm.2024.24.2.109. Epub 2024 Mar 28.