Inoue K, Nakajima T, Kato N
Jpn J Psychiatry Neurol. 1986 Jun;40(2):143-51. doi: 10.1111/j.1440-1819.1986.tb03136.x.
In an attempt to evaluate retrospectively the three-year course and outcome of treated adolescent schizophrenics, the medical data of 19 patients were collected from the first admissions over a period of 10 years (1971-1981). According to the DSM-III criteria, 17 were diagnosed as having schizophrenic disorders and the remaining 2 were schizophreniform disorders. The outcome at the time of first- to third-year follow-up was assessed on the outcome rating scale. The three-year outcome was favorable with respect to both the length of hospitalization and the presence of psychotic symptoms. However, there was a sustained impairment in occupational (or scholastic) functioning throughout the three-year follow-up period. The female sex and the initial diagnosis of schizophreniform disorder might be factors affecting the good third-year clinical (or symptomatic) outcome. The younger age at onset, the longer duration of the prodromal phase, and the longer period of time between the onset and the first presentation appeared to predict the poor third-year occupational outcome.
为了回顾性评估接受治疗的青少年精神分裂症患者的三年病程及转归，我们收集了19例患者在10年期间（1971 - 1981年）首次入院时的医学资料。根据《精神疾病诊断与统计手册第三版》（DSM - III）标准，17例被诊断为精神分裂症，其余2例为精神分裂症样障碍。在首次至第三年随访时，通过结局评定量表评估转归。就住院时间和精神病性症状而言，三年转归良好。然而，在整个三年随访期内，职业（或学业）功能持续受损。女性以及精神分裂症样障碍的初始诊断可能是影响第三年良好临床（或症状）转归的因素。起病年龄较小、前驱期持续时间较长以及起病与首次就诊之间的时间间隔较长似乎预示着第三年职业转归较差。
