Mukhtar Sonia, Moradi Ali, Kodali Athri, Okoye Chiugo, Klein Dhadon, Mohamoud Iman, Olanisa Olawale O, Parab Panah, Chaudhary Priti, Hamid Pousette
Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Medicine, Semmelweis University, Budapest, HUN.
Cureus. 2023 Sep 14;15(9):e45259. doi: 10.7759/cureus.45259. eCollection 2023 Sep.
This narrative review summarizes the principal findings of observational studies, systematic reviews, and meta-analyses on diet and dietary patterns' role in the risk of pancreatic cancer. Etiologically pancreatic cancer is multifactorial. Evidence exists of an association between nutrients, dietary patterns, and pancreatic cancer. An extensive literature search was conducted on PubMed, Cochrane, and Google Scholar. A thorough search of articles published in English till May 2023 and related to the review was performed. The relationship between all macronutrients, micronutrients, and various dietary patterns with the risk of pancreatic cancer was assessed. It is concluded that a diet high in nutrients like red and processed meat, refined sugars, saturated and monounsaturated fats, alcohol, copper, and a Western dietary pattern can increase the likelihood of pancreatic cancer. Contrary to this, a diet consisting of fruits, vegetables, appropriate quantities of vitamins and minerals, and a Mediterranean dietary pattern is associated with a decreased risk of pancreatic cancer.
这篇叙述性综述总结了观察性研究、系统评价和荟萃分析中关于饮食及饮食模式在胰腺癌风险中作用的主要发现。从病因学角度来看,胰腺癌是多因素导致的。有证据表明营养素、饮食模式与胰腺癌之间存在关联。我们在PubMed、Cochrane和谷歌学术上进行了广泛的文献检索。对截至2023年5月以英文发表且与该综述相关的文章进行了全面搜索。评估了所有宏量营养素、微量营养素以及各种饮食模式与胰腺癌风险之间的关系。得出的结论是,富含红肉和加工肉类、精制糖、饱和脂肪和单不饱和脂肪、酒精、铜等营养素的饮食以及西方饮食模式会增加患胰腺癌的可能性。与此相反,由水果、蔬菜、适量维生素和矿物质组成的饮食以及地中海饮食模式与降低胰腺癌风险相关。