Qadir Rana Muhammad Anss Bin, Umair Musab Bin, Tariq Umar Bin, Ahmad Arslan, Kiran Wajeeha, Shahid M Hasaan
Surgery, Queen's Hospital, Romford, GBR.
Surgery, Meriden Hospital, Conventry, GBR.
Cureus. 2024 Nov 1;16(11):e72816. doi: 10.7759/cureus.72816. eCollection 2024 Nov.
Pancreatic cancer is one of the most lethal malignancies, characterized by late diagnosis, rapid progression, and limited treatment options. This literature review comprehensively examines the epidemiology, risk factors, diagnostic challenges, treatment modalities, and prognosis of pancreatic cancer. It highlights the global disparities in incidence and outcomes, exploring the influence of socioeconomic, environmental, and genetic factors on disease progression. In addition, this review discusses recent advancements in diagnostic tools and treatment strategies, identifying gaps in current research and clinical practices. The synthesis aims to inform future research directions and policy-making efforts to reduce the global burden of pancreatic cancer and improve patient outcomes.
胰腺癌是最致命的恶性肿瘤之一,其特点是诊断较晚、进展迅速且治疗选择有限。这篇文献综述全面研究了胰腺癌的流行病学、危险因素、诊断挑战、治疗方式及预后。它突出了发病率和治疗结果方面的全球差异,探讨了社会经济、环境和遗传因素对疾病进展的影响。此外,本综述讨论了诊断工具和治疗策略的最新进展,找出了当前研究和临床实践中的差距。综合分析旨在为未来的研究方向和政策制定工作提供信息,以减轻全球胰腺癌负担并改善患者治疗结果。