Blaženka Kljaić Bukvić, MD, PhD, Department of Pediatrics General Hospital "Dr. Josip Benčević", Andrije Štampara 42, 35000 Slavonski Brod;
Acta Dermatovenerol Croat. 2023 Aug;31(1):3-10.
The aim of the study was to investigate the impact of atopic dermatitis (AD) in children and corticophobia on the quality of family life. Children with AD and their parents were included in a cross-sectional study. The severity of AD was self-assessed using the Patient Oriented-Scoring of Atopic Dermatitis (PO-SCORAD) index, and the severity of corticophobia using the Topical Corticosteroid Phobia (TOPICOP) score, and the general impact of AD on family quality of life using the Family Dermatology Life Quality Index (FDLQI). We included 330 parents, mostly mothers (99.4%) and children with a median age of 3 years (interquartile range, IQR 1.5-5.0 years). The median values of the PO SCORAD index and TOPICOP score were: 19.1 (IQR 13.6-24.1) and 58.3 (IQR 41.7-72.2), respectively. The median FDQLI score was 12 (IQR 7-16). The influence of independent variables such as parental age, child's age, child's gender, family history of allergies, place of residence, parental education, associated allergic disease in the child, PO SCORAD, and the TOPICOP score on the FDLQI was analysed. The significant models were the age of the parents (protective factor), the PO SCORAD index, and the TOPICOP score, which together accounted for 26.1% of the variability of FDLQI. Concusion of the study is that AD in children, its severity, and the parent's fear of chronic corticosteroid treatment impair the quality of family life.
本研究旨在探讨儿童特应性皮炎（AD）和皮质恐惧症对家庭生活质量的影响。采用特应性皮炎患者自评评分（PO-SCORAD）指数评估 AD 严重程度，采用皮质类固醇恐惧症评分（TOPICOP）评估皮质恐惧症严重程度，采用家庭皮肤病生活质量指数（FDLQI）评估 AD 对家庭生活质量的总体影响。我们纳入了 330 名父母，他们大多是母亲（99.4%），孩子的中位年龄为 3 岁（四分位距 IQR 1.5-5.0 岁）。PO-SCORAD 指数和 TOPICOP 评分的中位数分别为 19.1（IQR 13.6-24.1）和 58.3（IQR 41.7-72.2）。FDLQI 的中位数为 12（IQR 7-16）。分析了父母年龄、孩子年龄、孩子性别、家族过敏史、居住地点、父母教育程度、孩子合并的过敏性疾病、PO-SCORAD 和 TOPICOP 评分等独立变量对 FDLQI 的影响。有意义的模型是父母年龄（保护因素）、PO-SCORAD 指数和 TOPICOP 评分，它们共同解释了 FDLQI 变异性的 26.1%。该研究的结论是，儿童 AD 及其严重程度和父母对慢性皮质类固醇治疗的恐惧会损害家庭生活质量。
