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以患者为导向的特应性皮炎严重程度和生活质量评分(PO-SCORAD)与其他评估分数之间的相关性分析。

Analysis of correlations between patient-oriented SCORAD (PO-SCORAD) and other assessment scores of atopic dermatitis severity and quality of life.

作者信息

Coutanceau Christine, Stalder Jean-François

机构信息

A-Derma Laboratories, Pierre Fabre Dermocosmétique, Lavaur, France.

出版信息

Dermatology. 2014;229(3):248-55. doi: 10.1159/000365075. Epub 2014 Aug 29.

Abstract

OBJECTIVE

Self-assessment scores such as the Patient-Oriented Scoring of Atopic Dermatitis (PO-SCORAD) index being recommended by public health authorities for chronic disease management, we aimed at analysing correlations between PO-SCORAD and physician and patient assessment scores of atopic dermatitis (AD) severity and quality of life.

METHODS

We perfomed an observational study conducted in 12 European countries in 4,222 atopic patients aged ≥1 month and prescribed Exomega® emollient cream. AD severity was measured by the SCORAD index, PO-SCORAD, Patient-Oriented Eczema Measure (POEM) and Self-Administered Eczema Area and Severity Index (SA-EASI) scales, and patient and family quality of life by the Dermatology Life Quality Index (DLQI) and Dermatitis Family Questionnaire Impact (DFQI) scales, respectively. Their correlations were analysed.

RESULTS

PO-SCORAD was the only self-assessment score to be highly correlated with the SCORAD index and POEM (r ≥ 0.70). It was also the best correlated with the DLQI (r = 0.67) and DFQI (r = 0.56). After a 5-week treatment, SCORAD index and PO-SCORAD severity scores had decreased significantly by 60 and 56% (p < 0.0001), and quality of life had improved.

CONCLUSION

PO-SCORAD is better correlated with quality of life scales than other self-assessment scores.

摘要

目的

鉴于公共卫生当局推荐使用如特应性皮炎患者导向评分(PO-SCORAD)指数等自我评估分数来进行慢性病管理,我们旨在分析PO-SCORAD与医生对特应性皮炎(AD)严重程度的评估分数以及患者对AD严重程度和生活质量的评估分数之间的相关性。

方法

我们在12个欧洲国家对4222名年龄≥1个月且已开具Exomega®润肤霜处方的特应性患者进行了一项观察性研究。通过SCORAD指数、PO-SCORAD、患者导向性湿疹测量(POEM)和自我管理的湿疹面积和严重程度指数(SA-EASI)量表来测量AD的严重程度,分别通过皮肤病生活质量指数(DLQI)和皮炎家庭问卷影响(DFQI)量表来测量患者及其家庭的生活质量。分析它们之间的相关性。

结果

PO-SCORAD是唯一与SCORAD指数和POEM高度相关(r≥0.70)的自我评估分数。它与DLQI(r = 0.67)和DFQI(r = 0.56)的相关性也最佳。经过5周的治疗后,SCORAD指数和PO-SCORAD严重程度分数显著下降了60%和56%(p < 0.0001),生活质量得到了改善。

结论

与其他自我评估分数相比,PO-SCORAD与生活质量量表的相关性更好。

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