Ranft J, Lammersen T, Heidrich H
Klin Wochenschr. 1986 Oct 1;64(19):946-50.
Fourty patients with thrombangiitis obliterans were examined to find out whether in-vivo capillary microscopy can contribute to the establishment of a diagnosis. No capillary-microscopical signs could be detected that are exclusive to thrombangiitis obliterans. Nevertheless typical signs as capillary lengthening, capillary branching (53%) and haemorrhagic margin (75%) are of considerable differential-diagnostic value when it comes to distinguishing a case of thrombangiitis obliterans from a case of degenerative arterial occlusive disease. In a further series of examinations, the nailfold area of patients with progressive systemic scleroderma was examined by in-vivo capillary microscopy and with an ophthalmoscope. The coincidence of the findings between the two methods was 80% and more, so that the examination of the nailfold capillaries with an ophthalmoscope can aid verify the diagnosis of scleroderma. In patients with rheumatoid arthritis capillary tortuosities (85%), capillary branching (53%) and increased venule visibility (55%) often occur. These are unspecific signs. Typically capillary-microscopical symptoms for the disease are not detectable.
对40例血栓闭塞性脉管炎患者进行了检查，以确定活体毛细血管显微镜检查是否有助于诊断的确立。未检测到血栓闭塞性脉管炎所特有的毛细血管显微镜征象。然而，在将血栓闭塞性脉管炎病例与退行性动脉闭塞性疾病病例区分开来时，典型征象如毛细血管延长、毛细血管分支（53%）和出血边缘（75%）具有相当大的鉴别诊断价值。在另一系列检查中，通过活体毛细血管显微镜检查和检眼镜对进行性系统性硬化症患者的甲襞区域进行了检查。两种方法的检查结果相符率达80%及以上，因此用检眼镜检查甲襞毛细血管有助于硬皮病的诊断核实。类风湿关节炎患者常出现毛细血管迂曲（85%）、毛细血管分支（53%）和小静脉可见度增加（55%）。这些都是非特异性征象。未检测到该疾病典型的毛细血管显微镜症状。
