No Difference in Muscle Basal Oxygenation in a Bedridden Population Pre and Post Rehabilitation.

Long periods of bed rest for elderly population, due to a femur fracture event, can cause a deterioration in the muscular capacity. Therefore, monitoring of the muscle oxidative capacity in this fragile population is necessary to define the muscular oxidative metabolism state before and after a rehabilitation period. The time-domain near-infrared spectroscopy (TD-NIRS) technique enables the absolute values to be calculated for hemodynamic parameters such as oxy- (OHb), deoxy- (HHb), total- (tHb) haemoglobin, and tissue oxygen saturation (SO) of the muscular tissue. In this work, we have characterized vastus lateralis muscle hemodynamics during a baseline period at two different time points: after the surgery (PRE) and after 15 days of rehabilitation (POST). The mean values for the absolute values of the hemodynamic parameters were: OHb_PRE = 49.1 ± 14.1 μM; OHb_POST = 47.1 ± 13.4 μM; HHb_PRE = 28.3 ± 10.3 μM; HHb_POST = 26.7 ± 9.9 μM; tHb_PRE = 77.3 ± 23.6 μM; tHb_POST = 73.8 ± 21.4 μM; SO_PRE = 63.9 ± 4.0% and SO_POST = 64.9 ± 5.6%. The hemodynamic parameters did not show significant differences at both group and single subject level. These results suggest that for this kind of population, the baseline of the hemodynamic parameters is not the best one to consider to assess the rehabilitation progresses in terms of muscular oxidative metabolism.