社区药剂师对二甲双胍缓释片药物治疗知识的见解：一项横断面研究。
Insights Into Metformin XR Pharmacotherapy Knowledge Among Community Pharmacists: A Cross-Sectional Study.
作者信息
Jairoun Ammar Abdulrahman, Al-Hemyari Sabaa Saleh, Shahwan Moyad, Hassan Nageeb, Zyoud Sa'ed H, Jaber Ammar Ali Saleh, Al-Qirim Tariq
机构信息
Health and Safety Department, Dubai Municipality, Dubai, United Arab Emirates.
Discipline of Clinical Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia (USM), Pulau Pinang, Malaysia.
出版信息
Clin Med Insights Endocrinol Diabetes. 2023 Oct 14;16:11795514231203913. doi: 10.1177/11795514231203913. eCollection 2023.
BACKGROUND
There is a little knowledge on the extent to which healthcare providers understand and accept the professional recommendations and appropriate dosing strategy regarding metformin XR.
OBJECTIVES
To evaluate UAE community pharmacists' knowledge, attitude, and practices (KAP) concerning metformin XR.
METHODS
This is a cross-sectional research study conducted amongst licensed community pharmacists. The survey took place via a questionnaire and physical interviews were held. The survey used in this study included questions on demographics and questions on the participants' attitudes, knowledge and practices concerning metformin XR. The factors influencing KAP regarding metformin XR were examined via simple logistic regression analysis.
RESULTS
Threehundred fifty-three (n = 353) participants were recruited in the study. Independent pharmacies constituted 57.5% of this study sample and 42.5% were chain pharmacies. The average knowledge score about metformin XR tablets was 42.5% with a confidence interval (CI) of 95% [37.3%, 47.4]. Better knowledge scores on metformin XR tablets was observed in respondents aged ⩾40 years (OR 2.97, 95% CI 1.63-5.4), having greater than 10 years in terms of experience (OR 2.28; 95% CI 1.25-4.16) and pharmacist graduated from Regional or international universities (OR 2.08; 95% CI 1.34-3.24). About 78% (n = 275) of the participants believed that metformin XR tablets have better efficacy and 63.2% (n = 233) indicated that metformin IR was associated with greater adverse effects.
CONCLUSION
This study demonstrated a distinct gap in knowledge, attitude and practice pertaining to metformin XR among community pharmacists in the UAE. The community pharmacists need to enhance their practice by receiving accurate and reliable data to support their decision-making on the prescribing of metformin XR. The implementation of novel guidelines and evidence dissemination strategies may help bridge this gap.
背景
关于医疗服务提供者对二甲双胍缓释片（metformin XR）的专业建议和适当给药策略的理解与接受程度，目前了解甚少。
目的
评估阿联酋社区药剂师对二甲双胍缓释片的知识、态度和实践（KAP）。
方法
这是一项针对持牌社区药剂师开展的横断面研究。通过问卷调查进行，同时进行了现场访谈。本研究使用的调查问卷包括人口统计学问题以及关于参与者对二甲双胍缓释片的态度、知识和实践的问题。通过简单逻辑回归分析研究影响二甲双胍缓释片KAP的因素。
结果
本研究招募了353名参与者。独立药店占本研究样本的57.5%，连锁药店占42.5%。关于二甲双胍缓释片的平均知识得分是42.5%，95%置信区间（CI）为[37.3%，47.4%]。年龄≥40岁的受访者（比值比[OR]2.97，95%CI 1.63 - 5.4）、从业经验超过10年的受访者（OR 2.28；95%CI 1.25 - 4.16）以及毕业于地区或国际大学的药剂师（OR 2.08；95%CI 1.34 - 3.24）对二甲双胍缓释片的知识得分更高。约78%（n = 275）的参与者认为二甲双胍缓释片疗效更好，63.2%（n = 233）表示二甲双胍普通片（metformin IR）不良反应更多。
结论
本研究表明阿联酋社区药剂师在二甲双胍缓释片的知识、态度和实践方面存在明显差距。社区药剂师需要通过获取准确可靠的数据来加强实践，以支持他们在二甲双胍缓释片处方方面的决策。实施新的指南和证据传播策略可能有助于弥补这一差距。
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