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AUC-RPP：用于非房室模型药代动力学分析的基础计算机程序。

AUC-RPP: BASIC computer program for compartment model independent pharmacokinetic analysis.

作者信息

Ritschel W A

出版信息

Methods Find Exp Clin Pharmacol. 1986 Oct;8(10):633-40.

PMID:3784702
Abstract

A computer program in BASIC for compartment model independent analysis (AUC-RPP) is presented. The program is based on regression analysis of the terminal phase, the area under the curve and the area under the first moment curve. It is designed for i.v. constant rate infusion, i.v. push and extravascular administration. For the latter route a simple estimate on the absorption rate constant is performed.

摘要

介绍了一个用于房室模型独立分析（AUC-RPP）的BASIC计算机程序。该程序基于终末相、曲线下面积和一阶矩曲线下面积的回归分析。它适用于静脉恒速输注、静脉推注和血管外给药。对于后一种给药途径，对吸收速率常数进行了简单估计。

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