School of Nutrition and Dietetics, Acadia University, Wolfville, NS, B4P 2R6, Canada.
College of Kinesiology, University of Saskatchewan, Saskatoon, SK, S7N 5B2, Canada.
Eur J Appl Physiol. 2024 Apr;124(4):1097-1107. doi: 10.1007/s00421-023-05337-7. Epub 2023 Oct 17.
Hemp contains protein with high concentrations of the branched-chain amino acids leucine, isoleucine, and valine and oils that have anti-inflammatory properties. Our purpose was to investigate the effects of hemp supplementation during resistance training in trained young adults.
Males (n = 22, 29 ± 8y) and females (n = 12, 30 ± 9y) were randomized (double-blind) to receive 60 g/d of hemp (containing 40 g protein and 9 g oil) or 60 g/d of soy (matched for protein and calories) during eight weeks of resistance training (~ 4x/week). Before and after the intervention, participants were assessed for whole-body lean tissue and fat mass (dual-energy X-ray absorptiometry), regional muscle hypertrophy (ultrasound), strength (1-repetition maximum leg press, bench press, biceps curl), voluntary activation (interpolated twitch technique), resting twitch properties (single pulse; 0.5 ms) (before and after a fatigue test), markers of inflammation (Interleukin 6 and C-reactive protein), and bone resorption (urinary N-telopeptides).
Hemp supplementation increased elbow flexor muscle thickness in females (2.6 ± 0.4-3.1 ± 0.5 cm, p = 0.012) while soy supplementation increased elbow flexor muscle thickness in males (3.7 ± 0.4-4.0 ± 0.5 cm, p < 0.01). Twitch torque and rate of torque development were preserved after a fatigue test in males consuming hemp compared to males on soy (p < 0.001).
Overall, hemp provides some sex-specific beneficial effects on measures of muscle accretion and torque under fatiguing conditions in resistance trained young adults.
gov Identifier: NCT02529917, registered August 11, 2015.
大麻含有蛋白质，其支链氨基酸亮氨酸、异亮氨酸和缬氨酸浓度较高，且大麻油具有抗炎特性。我们的目的是研究在接受过阻力训练的年轻成年人中，补充大麻对阻力训练的影响。
男性（n=22，29±8 岁）和女性（n=12，30±9 岁）被随机（双盲）分配到接受 60g/d 的大麻（含有 40g 蛋白质和 9g 油）或 60g/d 的大豆（蛋白质和卡路里相匹配），在 8 周的阻力训练期间（~4 次/周）。在干预前后，通过双能 X 射线吸收法评估全身瘦组织和脂肪量，超声评估局部肌肉肥大，1 次重复最大腿部按压、卧推、二头肌卷曲评估力量，插值抽搐技术评估自愿激活，单脉冲（0.5ms）评估休息抽搐特性（疲劳试验前后），评估炎症标志物（白细胞介素 6 和 C 反应蛋白）和骨吸收（尿 N-端肽）。
大麻补充剂增加了女性的肘部屈肌肌肉厚度（2.6±0.4-3.1±0.5cm，p=0.012），而大豆补充剂增加了男性的肘部屈肌肌肉厚度（3.7±0.4-4.0±0.5cm，p<0.01）。与大豆组相比，食用大麻的男性在疲劳试验后，抽搐扭矩和扭矩发展率保持不变（p<0.001）。
总体而言，大麻对接受过阻力训练的年轻成年人的肌肉增生和疲劳条件下的扭矩测量有一些特定于性别的有益作用。
gov 标识符：NCT02529917，注册于 2015 年 8 月 11 日。
