Nakrys Marius, Valinskas Sarunas, Aleknavicius Kasparas, Jonusas Justinas
Kilo.Health, Vilnius, Lithuania.
Lithuania Business University of Applied Sciences, Klaipėda, Lithuania.
JMIR Cardio. 2023 Oct 17;7:e48454. doi: 10.2196/48454.
BACKGROUND: The high prevalence of hypertension necessitates effective, scalable interventions for blood pressure (BP) control. Self-monitoring has shown improved adherence to medication and better BP management. Mobile apps offer a promising approach with their increasing popularity and potential for large-scale implementation. Studies have demonstrated associations between mobile app interventions and lowered BP, yet real-world data on app effectiveness and engagement remain limited. OBJECTIVE: In this study, we analyzed real-world user data from the Cardi.Health mobile app, which is aimed at helping its users monitor and control their BP. Our goal was to find out whether there is an association between the use of the mobile app and a decrease in BP. Additionally, the study explored how engagement with the app may influence this outcome. METHODS: This was a retrospective chart review study. The initial study population comprised 4407 Cardi.Health users who began using the app between January 2022 and April 2022. After applying inclusion criteria, the final study cohort comprised 339 users with elevated BP at the baseline. The sample consisted of 108 (31.9%) men and 231 (68.1%) women (P=.04). This retrospective chart review study obtained permission from the Biomedical Research Alliance of New York Institutional Review Board (June 2022, registration ID 22-08-503-939). RESULTS: The study's main findings were that there is a possible relationship between use of the Cardi.Health mobile app and a decrease in systolic BP. Additionally, there was a significant association between active use of the app and systolic BP decrease (χ=5.311; P=.02). Finally, active users had an almost 2 times greater chance of reducing systolic BP by 5 mm Hg or more over 4 weeks (odds ratio 1.932, 95% CI 1.074-3.528; P=.03). CONCLUSIONS: This study shows a possible relationship between Cardi.Health mobile app use and decreased BP. Additionally, engagement with the app may be related to better results-active use was associated with an almost 2-fold increase in the odds of reducing BP by 5 or more mm Hg.
背景：高血压的高患病率需要有效的、可扩展的血压控制干预措施。自我监测已显示出改善了药物依从性并实现了更好的血压管理。移动应用程序因其日益普及和大规模实施的潜力而提供了一种很有前景的方法。研究表明移动应用程序干预与血压降低之间存在关联，但关于应用程序有效性和参与度的真实世界数据仍然有限。 目的：在本研究中，我们分析了Cardi.Health移动应用程序的真实世界用户数据，该应用程序旨在帮助用户监测和控制血压。我们的目标是找出使用移动应用程序与血压降低之间是否存在关联。此外，该研究还探讨了与应用程序的互动如何可能影响这一结果。 方法：这是一项回顾性图表审查研究。初始研究人群包括2022年1月至2022年4月开始使用该应用程序的4407名Cardi.Health用户。应用纳入标准后，最终研究队列包括339名基线血压升高的用户。样本包括108名（31.9%）男性和231名（68.1%）女性（P = 0.04）。这项回顾性图表审查研究获得了纽约生物医学研究联盟机构审查委员会的许可（2022年6月，注册号22 - 08 - 503 - 939）。 结果：该研究的主要发现是，使用Cardi.Health移动应用程序与收缩压降低之间可能存在关联。此外，积极使用该应用程序与收缩压降低之间存在显著关联（χ = 5.311；P = 0.02）。最后，在4周内，活跃用户将收缩压降低5毫米汞柱或更多的可能性几乎是其他用户的2倍（优势比1.932，95%置信区间1.074 - 3.528；P = 0.03）。 结论：本研究表明使用Cardi.Health移动应用程序与血压降低之间可能存在关联。此外，与应用程序的互动可能与更好的结果相关——积极使用与将血压降低5毫米汞柱或更多的几率几乎增加一倍有关。
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