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体重指数、颈围与高血压:一项前瞻性队列研究。

Body mass index, neck circumference, and hypertension: a prospective cohort study.

作者信息

Ren Tao-Jun, Zhang Kun, Li Wen-Juan, Ren Shu-Tang, Huang Yun-Zhou, Yang Ning, Wu Shou-Ling, Li Yu-Ming

机构信息

Clinical School of Cardiovascular Disease, Tianjin Medical University, Tianjin, China.

Department of Cardiology, TEDA International Cardiovascular Hospital, Tianjin, China.

出版信息

Front Cardiovasc Med. 2023 Oct 2;10:1269328. doi: 10.3389/fcvm.2023.1269328. eCollection 2023.

Abstract

OBJECTIVE

This study aimed to investigate the association between BMI combined with neck circumference and the risk of hypertension.

METHODS

We selected participants from the Kailuan study in 2014 who were normotensive as our research subjects. We compared the risk of hypertension among individuals in group 1 (non-obese with low neck circumference), group 2 (non-obese with high neck circumference), group 3 (obese with low neck circumference), and group 4 (obese with high neck circumference).

RESULTS

After a median observation period of 3.86 years, hypertension occurred in 13,383 participants. Subjects in Group 2, 3, and 4 had significantly higher risks of hypertension compared to Group 1, with hazard ratios (HRs) of 1.066 (95% CI: 1.025, 1.110), 1.322 (95% CI: 1.235, 1.415), and 1.422 (95% CI: 1.337, 1.512), respectively. Additionally, adding BMI to a conventional model had a greater incremental effect on predicting hypertension compared to adding neck circumference alone. However, considering both BMI and neck circumference together further improved the prediction of hypertension.

CONCLUSION

Individuals with both high BMI and high neck circumference face a higher risk of hypertension. Moreover, BMI is a superior predictor of hypertension risk compared to neck circumference, but using both of these measures can further enhance the accuracy of hypertension risk prediction.

摘要

目的

本研究旨在探讨体重指数(BMI)与颈围相结合与高血压风险之间的关联。

方法

我们从2014年开滦研究中选取血压正常者作为研究对象。我们比较了第1组(非肥胖且颈围低)、第2组(非肥胖且颈围高)、第3组(肥胖且颈围低)和第4组(肥胖且颈围高)个体患高血压的风险。

结果

经过3.86年的中位观察期后,13383名参与者发生了高血压。与第1组相比,第2、3和4组的受试者患高血压的风险显著更高,风险比(HR)分别为1.066(95%置信区间:1.025,1.110)、1.322(95%置信区间:1.235,1.415)和1.422(95%置信区间:1.337,1.512)。此外,与单独添加颈围相比,在传统模型中添加BMI对预测高血压具有更大的增量效应。然而,同时考虑BMI和颈围可进一步改善对高血压的预测。

结论

BMI高且颈围高的个体面临更高的高血压风险。此外,与颈围相比,BMI是高血压风险的更好预测指标,但同时使用这两种测量方法可进一步提高高血压风险预测的准确性。

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