Li Peng, Zhou Jihe
Graduate School of Chengdu Sports University, Chengdu Sports University, Chengdu, China.
School of Physical Education and Health, Zunyi Medical University, Zunyi, China.
Front Chem. 2023 Oct 2;11:1273726. doi: 10.3389/fchem.2023.1273726. eCollection 2023.
For professional athletes or fitness crowd who often participate in sports, sports injury are more common. However, the traditional repair materials for sports injury have many problems, such as long recovery period and poor repair effect. In recent years, many studies have found that conjugated materials have good stability, small side effects and other excellent characteristics, and conjugated materials are used in sports injury repair materials. In order to study the repair effect of conjugated materials on sports injury tissues, this paper prepared nitrogen porphyrin conjugated organic skeleton materials with pyrrole and p-benzaldehyde as substrates, used chemical synthesis and selective laser sintering technology to form plastic conjugated scaffold materials with polyvinyl alcohol, polylactide and conjugated materials, and established mechanical properties and constitutive formula to evaluate the performance characteristics of repair materials. In order to test the effect of plastic conjugated materials on sports injury, experiments were carried out from the aspects of degradability, mechanical properties of repair materials, repair effect of radius defect and new bone formation area. Experimental data: The proportion of newly formed bone area at weeks 3, 6, and 9 using this method was 32%, 52%, and 68%, while the proportion of newly formed bone area at weeks 3, 6, and 9 using traditional methods was 12%, 18%, and 23%, indicating that this method had better bone repair effects than traditional methods. The research in this paper provided a new idea for the application of plastic conjugated materials in the field of sports medicine.
对于经常参加运动的职业运动员或健身人群来说,运动损伤更为常见。然而,传统的运动损伤修复材料存在诸多问题,如恢复期长、修复效果不佳等。近年来,许多研究发现共轭材料具有稳定性好、副作用小等优异特性,且共轭材料被应用于运动损伤修复材料中。为了研究共轭材料对运动损伤组织的修复效果,本文以吡咯和对苯二甲醛为底物制备了氮卟啉共轭有机骨架材料,采用化学合成和选择性激光烧结技术,与聚乙烯醇、聚乳酸及共轭材料形成塑性共轭支架材料,并建立力学性能和本构方程来评估修复材料的性能特征。为了测试塑性共轭材料对运动损伤的作用效果,从降解性、修复材料的力学性能、桡骨缺损修复效果及新骨形成面积等方面进行了实验。实验数据:采用该方法在第3周、第6周和第9周时新形成骨面积的比例分别为32%、52%和68%,而采用传统方法在第3周、第6周和第9周时新形成骨面积的比例分别为12%、18%和23%,表明该方法的骨修复效果优于传统方法。本文的研究为塑性共轭材料在运动医学领域的应用提供了新思路。