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青少年女性多囊卵巢综合征的患病率及其与肥胖的关联。

Prevalence of Polycystic Ovarian Syndrome and Its Link to Obesity in Adolescent Girls.

作者信息

Aggarwal Muskan, Chakole Swarupa

机构信息

Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

Community Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

出版信息

Cureus. 2023 Sep 17;15(9):e45405. doi: 10.7759/cureus.45405. eCollection 2023 Sep.

Abstract

Polycystic ovarian syndrome (PCOS), also referred to as Stein-Leventhal syndrome, happens to be one of most common hormonal disorders found in females, causing large-sized ovaries with small cysts of non-ovulated oocytes in the outer medulla part of the ovary. Women suffering from PCOS often exhibit symptoms like oligomenorrhoea, elevated testosterone levels, acne, alopecia, hirsutism, sudden weight gain and many more. It can predispose a woman to developing infertility in future, and thus, difficulties in conceiving; due to the cystic changes in the ovaries, it results in anovulation and amenorrhea. The early symptoms of PCOS are being commonly observed nowadays in young women who are in their early 20s and those who are overweight or obese. The metabolic expression of PCOS increases with obesity. Obesity is a factor that is considered to contribute the most in the occurrence of various long-standing and non-transmissible illnesses apart from PCOS such as atherosclerosis, hypertension, diabetes, high blood cholesterol and even certain types of cancers. In obesity, there is an increase in the size and number of fat cells in the body. Obese and overweight young girls have a heightened likelihood of developing PCOS and its corresponding metabolic and reproductive health complications.

摘要

多囊卵巢综合征(PCOS),也被称为斯坦因-莱文塔尔综合征,是女性中最常见的激素紊乱疾病之一,会导致卵巢增大,在卵巢外髓质部分出现未排卵卵母细胞的小囊肿。患有PCOS的女性通常会出现月经过少、睾酮水平升高、痤疮、脱发、多毛、体重突然增加等症状。它会使女性未来易患不孕症,从而导致受孕困难;由于卵巢的囊性变化,会导致无排卵和闭经。如今,在20岁出头的年轻女性以及超重或肥胖的女性中,PCOS的早期症状很常见。PCOS的代谢表现会随着肥胖而增加。肥胖是一个被认为除了PCOS之外,在各种长期和非传染性疾病如动脉粥样硬化、高血压、糖尿病、高胆固醇血症甚至某些类型癌症的发生中贡献最大的因素。在肥胖状态下,体内脂肪细胞的大小和数量会增加。肥胖和超重的年轻女孩患PCOS及其相应代谢和生殖健康并发症的可能性更高。

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本文引用的文献

2
What do we know about metabolic syndrome in adolescents with PCOS?我们对患有多囊卵巢综合征的青少年的代谢综合征了解多少?
J Turk Ger Gynecol Assoc. 2014 Mar 1;15(1):49-55. doi: 10.5152/jtgga.2014.95776. eCollection 2014.
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Childhood obesity and its impact on the development of adolescent PCOS.儿童肥胖及其对青少年 PCOS 发展的影响。
Semin Reprod Med. 2014 May;32(3):202-13. doi: 10.1055/s-0034-1371092. Epub 2014 Apr 8.
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Prevalence of polycystic ovary syndrome in adolescents.多囊卵巢综合征在青少年中的流行情况。
Fertil Steril. 2013 Aug;100(2):470-7. doi: 10.1016/j.fertnstert.2013.04.001. Epub 2013 Jun 5.
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Horm Res Paediatr. 2012;78(5-6):269-78. doi: 10.1159/000345310. Epub 2012 Nov 28.
8
Obesity and PCOS: implications for diagnosis and treatment.肥胖与多囊卵巢综合征:对诊断与治疗的影响。
Semin Reprod Med. 2012 Dec;30(6):496-506. doi: 10.1055/s-0032-1328878. Epub 2012 Oct 16.

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