Contento Jacqueline, Cleveland Vincent, Ehtiati Tina, Olivieri Laura, Kanter Joshua
Division of Pediatric Cardiology, Children's National Hospital, Washington, District of Columbia, USA.
Advanced Therapies, Siemens Medical Solutions USA, Inc., Malvern, Pennsylvania, USA.
Catheter Cardiovasc Interv. 2023 Nov;102(6):1109-1113. doi: 10.1002/ccd.30862. Epub 2023 Oct 19.
Endomyocardial biopsy (EMB) of the right ventricular (RV) septal surface during cardiac catheterization is the standard method to assess cardiac allograft rejection, heart failure, or inflammatory cardiomyopathies. We developed methodology using a three-dimensional (3D) printed phantom to provide proof of concept for using biplane overlay technology for targeted EMB. A standard bioptome and steerable sheath were used to discern feasibility of biopsy for seven regions of the RV septum guided by 3D overlay. This novel biopsy phantom can help train operators in biopsy techniques, and biplane overlay technology has the potential to advance targeted EMB in transplant and cardiomyopathy populations.
心脏导管插入术期间对右心室(RV)间隔表面进行心内膜心肌活检(EMB)是评估心脏移植排斥反应、心力衰竭或炎性心肌病的标准方法。我们开发了一种使用三维(3D)打印模型的方法,以提供使用双平面叠加技术进行靶向EMB的概念验证。使用标准活检钳和可操纵鞘管,在3D叠加引导下辨别右心室间隔七个区域活检的可行性。这种新型活检模型有助于培训操作人员的活检技术,双平面叠加技术有潜力在移植和心肌病患者群体中推进靶向EMB。