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科尔萨科夫综合征患者和酗酒者在关联性记忆的动物实验任务中存在严重缺陷。

Korsakoff and alcoholic subjects are severely impaired in animal tasks of associative memory.

作者信息

Kessler J, Irle E, Markowitsch H J

出版信息

Neuropsychologia. 1986;24(5):671-80. doi: 10.1016/0028-3932(86)90006-0.

Abstract

Korsakoff subjects, members of the Alcoholics Anonymous, and alcoholics with 1 week or 5-6 months of abstinence were tested in a concurrent object discrimination task with 10 and 20 pairs of objects and compared to control subjects matched for age and education. The anonymous alcoholics were moderately Korsakoff subjects strongly impaired, whereas alcoholics with 1 week or 5-6 months abstinence performed similar to control subjects. The results are discussed with respect to current research on human amnesia and comparative neuropsychological topics.

摘要

对科萨科夫综合征患者、戒酒互助会成员以及戒酒1周或5 - 6个月的酗酒者进行了一项同时进行的客体辨别任务测试,该任务中有10对和20对客体,并与年龄和教育程度相匹配的对照组受试者进行比较。匿名酗酒者表现中度受损,科萨科夫综合征患者严重受损,而戒酒1周或5 - 6个月的酗酒者表现与对照组受试者相似。结合当前关于人类失忆症和比较神经心理学主题的研究对结果进行了讨论。

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