Golbe L I, Merkin M D
Neurology. 1986 Dec;36(12):1602-4. doi: 10.1212/wnl.36.12.1602.
After smoking "crack," the free-base form of cocaine, a 27-year-old man suffered an infarction of most of the territory of the right middle cerebral artery. Concomitant drug use seemed to have been limited to ethanol and ibuprofen. Search for other possible causes was negative. Angiography revealed narrowing of the supraclinoid portion of the right internal carotid artery (ICA) and cutoff of at least two distal branches. There was no beading or irregularity to suggest vasculitis. Crack may have induced vasospasm in the ICA through recognized sympathomimetic actions of cocaine.
吸食“快克”（可卡因的游离碱形式）后，一名27岁男子右侧大脑中动脉大部分区域发生梗死。同时使用的药物似乎仅限于乙醇和布洛芬。寻找其他可能病因的检查结果为阴性。血管造影显示右侧颈内动脉（ICA）鞍上部分狭窄，至少两个远端分支中断。未见串珠样改变或不规则表现提示血管炎。快克可能通过可卡因公认的拟交感神经作用诱发了颈内动脉血管痉挛。
