• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Does serotonin matter in depression?

作者信息

Albert Paul R, Blier Pierre

机构信息

The Ottawa Hospital Research Institute, University of Ottawa (Albert); and the Institute for Mental Health Research, Royal Ottawa Mental Health Centre (Blier), Ottawa, Ont., Canada

The Ottawa Hospital Research Institute, University of Ottawa (Albert); and the Institute for Mental Health Research, Royal Ottawa Mental Health Centre (Blier), Ottawa, Ont., Canada.

出版信息

J Psychiatry Neurosci. 2023 Oct 19;48(5):E400-E403. doi: 10.1503/jpn.230130. Print 2023 Sep-Oct.

DOI:10.1503/jpn.230130
PMID:37857415
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10599657/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6673/10599657/bbadec2706aa/48-5-e400f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6673/10599657/bbadec2706aa/48-5-e400f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6673/10599657/bbadec2706aa/48-5-e400f1.jpg

相似文献

1
Does serotonin matter in depression?血清素在抑郁症中起重要作用吗?
J Psychiatry Neurosci. 2023 Oct 19;48(5):E400-E403. doi: 10.1503/jpn.230130. Print 2023 Sep-Oct.
2
Selective serotonin reuptake inhibitors versus tricyclic and heterocyclic antidepressants: comparison of drug adherence.选择性5-羟色胺再摄取抑制剂与三环类及杂环类抗抑郁药:药物依从性比较
Cochrane Database Syst Rev. 2000(4):CD002791. doi: 10.1002/14651858.CD002791.
3
WITHDRAWN: Treatment discontinuation with selective serotonin reuptake inhibitors (SSRIs) versus tricyclic antidepressants (TCAs).撤回:选择性5-羟色胺再摄取抑制剂(SSRI)与三环类抗抑郁药(TCA)停药情况对比
Cochrane Database Syst Rev. 2007 Jul 18(3):CD002791. doi: 10.1002/14651858.CD002791.pub2.
4
Antidepressant drugs: does it matter if they inhibit the reuptake of noradrenaline or serotonin?抗抑郁药:抑制去甲肾上腺素或5-羟色胺的再摄取有关系吗?
Acta Psychiatr Scand Suppl. 2000;402:12-7. doi: 10.1034/j.1600-0447.2000.00003.x.
5
[Neuroadaptive changes in brain during selective serotonin reuptake inhibitors action].[选择性5-羟色胺再摄取抑制剂作用期间大脑的神经适应性变化]
Ross Fiziol Zh Im I M Sechenova. 2007 Nov;93(11):1245-51.
6
[Apathy syndrome in depressed patients previously treated with selective serotonin reuptake inhibitors].[曾接受选择性5-羟色胺再摄取抑制剂治疗的抑郁症患者的淡漠综合征]
Zh Nevrol Psikhiatr Im S S Korsakova. 2020;120(1):111-117. doi: 10.17116/jnevro2020120011111.
7
Should selective serotonin reuptake inhibitors be prescribed to all patients with ischemic heart disease?是否应该给所有缺血性心脏病患者开选择性5-羟色胺再摄取抑制剂?
Curr Psychiatry Rep. 2004 Jun;6(3):202-9. doi: 10.1007/s11920-004-0065-1.
8
Serotonin reuptake inhibitors and breastfeeding: a systematic review.血清素再摄取抑制剂与母乳喂养:一项系统综述
Hum Psychopharmacol. 2015 Jan;30(1):4-20. doi: 10.1002/hup.2451.
9
Selective serotonin reuptake inhibitors for depression?用于治疗抑郁症的选择性5-羟色胺再摄取抑制剂?
Drug Ther Bull. 1993 Jul 19;31(15):57-8.
10
Selective serotonin reuptake inhibitors.选择性5-羟色胺再摄取抑制剂
Lippincott Health Promot Lett. 1997 Nov-Dec;2(10):5.

引用本文的文献

1
Serotonin Receptors in Areas of the Emotion Regulation Network in Human and Rat Brains-A Comparative Autoradiographic Study.人类和大鼠大脑情绪调节网络区域中的血清素受体——一项比较放射自显影研究
J Comp Neurol. 2025 Jul;533(7):e70068. doi: 10.1002/cne.70068.
2
In vivo serotonin 1A receptor distribution in treatment-resistant depression.难治性抑郁症中5-羟色胺1A受体的体内分布
Transl Psychiatry. 2025 Jun 3;15(1):186. doi: 10.1038/s41398-025-03406-3.
3
Associations between appetite loss and clinical features as well as inflammatory cytokines in adolescents with major depressive disorder.

本文引用的文献

1
How should we design future mechanistic and/or efficacy clinical trials?我们应该如何设计未来的机制和/或疗效临床试验?
Neuropsychopharmacology. 2024 Jan;49(1):197-204. doi: 10.1038/s41386-023-01600-9. Epub 2023 May 26.
2
Brain Serotonin Release Is Reduced in Patients With Depression: A [C]Cimbi-36 Positron Emission Tomography Study With a d-Amphetamine Challenge.抑郁症患者脑内血清素释放减少:一项使用 [C]西苯三嗪正电子发射断层扫描研究和 d-苯丙胺挑战的研究。
Biol Psychiatry. 2023 Jun 15;93(12):1089-1098. doi: 10.1016/j.biopsych.2022.10.012. Epub 2022 Oct 29.
3
The serotonin theory of depression: a systematic umbrella review of the evidence.
重度抑郁症青少年食欲减退与临床特征及炎性细胞因子之间的关联。
Front Psychiatry. 2025 May 14;16:1583060. doi: 10.3389/fpsyt.2025.1583060. eCollection 2025.
4
From Stress to Synapse: The Neuronal Atrophy Pathway to Mood Dysregulation.从应激到突触:神经元萎缩导致情绪失调的途径。
Int J Mol Sci. 2025 Mar 30;26(7):3219. doi: 10.3390/ijms26073219.
5
Depression and Anxiety in Patients with Psoriasis: A Comprehensive Analysis Combining Bibliometrics, Latent Dirichlet Allocation, and HJ-Biplot.银屑病患者的抑郁与焦虑:结合文献计量学、潜在狄利克雷分配和HJ-双标图的综合分析
Healthcare (Basel). 2025 Feb 20;13(5):441. doi: 10.3390/healthcare13050441.
6
Can Vıtamın D Reduce the Need for SSRI by Modulatıng Serotonın Synthesıs?: A Revıew of Recent Lıterature.维生素D能否通过调节血清素合成减少对选择性5-羟色胺再摄取抑制剂(SSRI)的需求?近期文献综述
Curr Nutr Rep. 2025 Mar 1;14(1):39. doi: 10.1007/s13668-025-00630-7.
7
Mental Health and Well-Being in the Modern Era: A Comprehensive Review of Challenges and Interventions.现代社会中的心理健康与幸福:挑战与干预措施的全面综述
Cureus. 2025 Jan 19;17(1):e77683. doi: 10.7759/cureus.77683. eCollection 2025 Jan.
8
Dynamics of human serotonin synthesis differentially link to reward anticipation and feedback.人类血清素合成的动力学与奖励预期和反馈存在不同的关联。
Mol Psychiatry. 2025 Feb;30(2):600-607. doi: 10.1038/s41380-024-02696-1. Epub 2024 Aug 23.
抑郁的 5-羟色胺理论:证据的系统伞状评价。
Mol Psychiatry. 2023 Aug;28(8):3243-3256. doi: 10.1038/s41380-022-01661-0. Epub 2022 Jul 20.
4
Psychedelic Psychiatry's Brave New World.迷幻精神病学的勇敢新世界。
Cell. 2020 Apr 2;181(1):24-28. doi: 10.1016/j.cell.2020.03.020.
5
Plasma serotonin levels are associated with antidepressant response to SSRIs.血浆血清素水平与 SSRIs 抗抑郁反应相关。
J Affect Disord. 2019 May 1;250:65-70. doi: 10.1016/j.jad.2019.02.063. Epub 2019 Feb 26.
6
A systematic review into the incidence, severity and duration of antidepressant withdrawal effects: Are guidelines evidence-based?一项关于抗抑郁药戒断效应的发生率、严重程度和持续时间的系统评价:指南是否基于证据?
Addict Behav. 2019 Oct;97:111-121. doi: 10.1016/j.addbeh.2018.08.027. Epub 2018 Sep 4.
7
Higher 5-HT autoreceptor binding as an endophenotype for major depressive disorder identified in high risk offspring - A pilot study.高风险后代中 5-羟色胺自身受体结合升高可作为重度抑郁症的内表型——一项初步研究。
Psychiatry Res Neuroimaging. 2018 Jun 30;276:15-23. doi: 10.1016/j.pscychresns.2018.04.002. Epub 2018 Apr 13.
8
Quantification of 5-HT and 5-HT receptor Binding in Depressed Suicide Attempters and Non-Attempters.对抑郁症自杀未遂者和非未遂者 5-HT 和 5-HT 受体结合的定量研究。
Arch Suicide Res. 2019 Jan-Mar;23(1):122-133. doi: 10.1080/13811118.2017.1417185. Epub 2018 Mar 5.
9
The functional serotonin 1a receptor promoter polymorphism, rs6295, is associated with psychiatric illness and differences in transcription.功能性5-羟色胺1a受体启动子多态性rs6295与精神疾病及转录差异相关。
Transl Psychiatry. 2016 Mar 1;6(3):e746. doi: 10.1038/tp.2015.226.
10
Fluoxetine: a case history of its discovery and preclinical development.氟西汀:其发现和临床前开发的案例历史。
Expert Opin Drug Discov. 2014 May;9(5):567-78. doi: 10.1517/17460441.2014.907790. Epub 2014 Apr 16.