Hajishoreh Negar Karimi, Jamalpoor Zahra, Rasouli Ramin, Asl Amir Nezami, Sheervalilou Roghayeh, Akbarzadeh Abolfazl
Health Research Center Chamran Hospital, Tehran, Iran.
Trauma research center, Aja University of Medical Sciences, Tehran, Iran.
Exp Cell Res. 2023 Dec 15;433(2):113821. doi: 10.1016/j.yexcr.2023.113821. Epub 2023 Oct 17.
Since the skin is the first barrier of the body's defense against pathogens, delays in the healing process are affected by infections. Therefore, applying advanced substitute assistance improves the patient's quality of life. Carbon-based nanomaterials show better capabilities than conventional methods for managing skin wound infections. Due to their physicochemical properties such as small size, large surface area, great surface-to-volume ratio, and excellent ability to communicate with the cells and tissue, carbon-based nanoparticles have been considered in regenerative medicine. moreover, the carbon nano family offers attractive potential in wound healing via the improvement of angiogenesis and antibacterial compared to traditional approaches become one of the particular research interests in the field of skin tissue engineering. This review emphasizes the wound-healing process and the role of carbon-based nanoparticles in wound care management interaction with tissue engineering technology.
由于皮肤是人体抵御病原体的第一道防线，愈合过程的延迟会受到感染的影响。因此，应用先进的替代辅助手段可提高患者的生活质量。碳基纳米材料在处理皮肤伤口感染方面比传统方法表现出更好的能力。由于其具有诸如尺寸小、表面积大、表面体积比大以及与细胞和组织良好的通讯能力等物理化学性质，碳基纳米粒子已被应用于再生医学。此外，与传统方法相比，碳纳米家族通过改善血管生成和抗菌作用在伤口愈合方面具有诱人的潜力，成为皮肤组织工程领域特别的研究热点之一。本综述着重阐述伤口愈合过程以及碳基纳米粒子在伤口护理管理中与组织工程技术相互作用的作用。
