Characterisation of saponins from in Vietnam northwest mountainous areas with the aid of high-resolution mass spectrometry.

This research aims to explore the saponins composition of in four northwest mountainous areas of Vietnam including Ha Giang, Lai Chau, Lao Cai, and Lang Son with the aid of high-resolution mass spectrometry. As a result, 42 saponins are successfully identified in leaves by UHPLC-Q-TOF-MS/MS analyses, in which two 30-noroleanane and four oleanane triterpene saponins structures have been reported for the first time. Two structures of were discovered in four samples. Two structures of were found in from Ha Giang and Lao Cai, while two structures of were not observed in Lang Son. Different environmental and climatic circumstances in various places may have an impact on chemical constituents of . By providing the phytochemicals profile of leaves, our study supports the orientation for future research on this medicinal plant as well as other species.