Pham Hong Ngoc, Tran Chieu An, Trinh Thi Diep, Nguyen Thi Ngoc Lan, Tran Phan Huynh Nhu, Le Van Nhan, Le Ngoc Hung, Phung Van Trung
Center for Research and Technology Transfer, Vietnam Academy of Science and Technology (VAST), Hanoi 100000, Vietnam.
Da Lat University, Dalat 66000, Lam Dong, Vietnam.
J Anal Methods Chem. 2022 Aug 8;2022:1167265. doi: 10.1155/2022/1167265. eCollection 2022.
has been reported to contain a wide range of metabolites and produce many pharmacological effects. This research demonstrates the determination and evaluation of the phytochemical profiling of grown in central Vietnam. Methanolic extract of ivy had been analyzed by ultra-high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UHPLC-Q-TOF-MS/MS). MS, and MS/MS experiments were manipulated using both negative and positive ionization modes to provide molecular mass information and production spectra for the structural elucidation of compounds. A total of 46 compounds including 24 triterpene saponins and other compounds were successfully identified of which four established saponin structures have been reported for the first time. This study has provided a base for building a quality control of the raw materials according to the profile of triterpene saponins and assessment of pharmaceutical ingredients of planted in Vietnam.
据报道，其含有多种代谢物并产生多种药理作用。本研究展示了对生长在越南中部的[植物名称未给出]的植物化学图谱的测定和评估。常春藤的甲醇提取物已通过超高效液相色谱 - 四极杆飞行时间质谱（UHPLC - Q - TOF - MS/MS）进行分析。质谱和串联质谱实验在负离子和正离子模式下进行操作，以提供分子量信息和产物光谱用于化合物的结构解析。总共成功鉴定出46种化合物，包括24种三萜皂苷和其他化合物，其中四种已确定的皂苷结构首次被报道。本研究为根据三萜皂苷图谱建立原材料质量控制以及评估在越南种植的[植物名称未给出]的药用成分提供了基础。
