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SWADESH:一个多模态多病种脑成像与神经心理学数据库及数据分析平台。

SWADESH: a multimodal multi-disease brain imaging and neuropsychological database and data analytics platform.

作者信息

Mandal Pravat K, Jindal Komal, Roy Saurav, Arora Yashika, Sharma Shallu, Joon Shallu, Goel Anshika, Ahasan Zoheb, Maroon Joseph C, Singh Kuldeep, Sandal Kanika, Tripathi Manjari, Sharma Pooja, Samkaria Avantika, Gaur Shradha, Shandilya Sandhya

机构信息

Neuroimaging and Neurospectroscopy (NINS) Laboratory, National Brain Research Centre, Gurgaon, India.

Florey Institute of Neuroscience and Mental Health, Melbourne School of Medicine Campus, Melbourne, VIC, Australia.

出版信息

Front Neurol. 2023 Oct 4;14:1258116. doi: 10.3389/fneur.2023.1258116. eCollection 2023.

Abstract

Multimodal neuroimaging data of various brain disorders provides valuable information to understand brain function in health and disease. Various neuroimaging-based databases have been developed that mainly consist of volumetric magnetic resonance imaging (MRI) data. We present the comprehensive web-based neuroimaging platform "SWADESH" for hosting multi-disease, multimodal neuroimaging, and neuropsychological data along with analytical pipelines. This novel initiative includes neurochemical and magnetic susceptibility data for healthy and diseased conditions, acquired using MR spectroscopy (MRS) and quantitative susceptibility mapping (QSM) respectively. The SWADESH architecture also provides a neuroimaging database which includes MRI, MRS, functional MRI (fMRI), diffusion weighted imaging (DWI), QSM, neuropsychological data and associated data analysis pipelines. Our final objective is to provide a master database of major brain disease states (neurodegenerative, neuropsychiatric, neurodevelopmental, and others) and to identify characteristic features and biomarkers associated with such disorders.

摘要

各种脑部疾病的多模态神经影像数据为理解健康和疾病状态下的脑功能提供了有价值的信息。已经开发了各种基于神经影像的数据库,这些数据库主要由容积磁共振成像(MRI)数据组成。我们展示了基于网络的综合神经影像平台“SWADESH”,用于存储多疾病、多模态神经影像和神经心理学数据以及分析流程。这一创新举措包括分别使用磁共振波谱(MRS)和定量磁化率映射(QSM)获取的健康和患病状态下的神经化学和磁化率数据。SWADESH架构还提供了一个神经影像数据库,其中包括MRI、MRS、功能磁共振成像(fMRI)、扩散加权成像(DWI)、QSM、神经心理学数据以及相关的数据分析流程。我们的最终目标是提供一个主要脑部疾病状态(神经退行性、神经精神性、神经发育性及其他)的主数据库,并识别与这些疾病相关的特征和生物标志物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbf9/10582723/b7fbd5beafbf/fneur-14-1258116-g001.jpg

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