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与出血性脑血管意外相关的风险因素:秘鲁一家医院患者的横断面研究。

Risk factors associated with hemorrhagic cerebrovascular accident: A cross-sectional study in patients from a hospital in Peru.

机构信息

Epidemiological Research Sciences, Vice Rectorado de Investigación, Universidad Privada Norbert Wiener, Lima, Peru.

Escuela Profesional de Tecnología Médica, Universidad Continental, Lima, Perú.

出版信息

Medicine (Baltimore). 2023 Oct 20;102(42):e35635. doi: 10.1097/MD.0000000000035635.

Abstract

In Peru, cardiovascular accidents (CVA) cause around 15% of premature death, with an increase in CVA due to the prevalence of risk factors for CVA in the Peruvian population. Hemorrhagic CVA presents higher mortality compared to ischemic. This research aimed to identify the risk factors associated with hemorrhagic CVA. We carried out a retrospective cross-sectional study using the medical records of patients with a diagnosis of CVA treated at the Regional Hospital of Ica during the years 2018 and 2019. Independent variables included age, sex, type 2 diabetes, dyslipidemia, hypertension, smoking, obesity, and intracranial carotid artery calcification. To identify factors associated with an increased probability for hemorrhagic CVA compared to ischemic CVA, a generalized linear model with logit link and binomial family, obtaining the odds ratio (OR) and its 95% confidence interval (CI). we evaluated the data from 132 patients. Of them, 46 (34.85%) had hemorrhagic CVA. Only systolic blood pressure (OR: 1.04; 95% CI: 1.02-1.06) and hypertension (OR: 0.29; 95% CI: 0.10-0.89) were significantly associated with hemorrhagic CVA compared to ischemic CVA. Hypertension is associated with hemorrhagic CVA compared to ischemic CVA. These results are consistent with the literature.

摘要

在秘鲁,心血管疾病(CVA)导致约 15%的人过早死亡,由于 CVA 的危险因素在秘鲁人群中普遍存在,CVA 的发病率有所增加。与缺血性 CVA 相比,出血性 CVA 的死亡率更高。本研究旨在确定与出血性 CVA 相关的危险因素。我们使用 2018 年至 2019 年在伊卡地区医院治疗的 CVA 患者的病历进行了回顾性横断面研究。独立变量包括年龄、性别、2 型糖尿病、血脂异常、高血压、吸烟、肥胖和颅内颈动脉钙化。为了确定与缺血性 CVA 相比出血性 CVA 发生概率增加相关的因素,我们使用对数链接和二项式家族的广义线性模型,得出优势比(OR)及其 95%置信区间(CI)。我们评估了 132 名患者的数据。其中,46 名(34.85%)患有出血性 CVA。与缺血性 CVA 相比,只有收缩压(OR:1.04;95%CI:1.02-1.06)和高血压(OR:0.29;95%CI:0.10-0.89)与出血性 CVA 显著相关。与缺血性 CVA 相比,高血压与出血性 CVA 相关。这些结果与文献一致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/775e/10589525/a30dcde55ce6/medi-102-e35635-g001.jpg

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