Youjiang Medical University for Nationalities, Youjiang, China.
China Institute for History of Medicine and Medical Literature, China Academy of Chinese Medical Sciences, Beijing, China.
Medicine (Baltimore). 2023 Oct 20;102(42):e35000. doi: 10.1097/MD.0000000000035000.
To compare the advantages and disadvantages of different acupuncture and moxibustion methods by network meta-analysis, in order to find out the best acupuncture and moxibustion adjuvant chemotherapy scheme of non-small cell lung cancer (NSCLC).
Randomized controlled trials of acupuncture and moxibustion adjuvant chemotherapy in the treatment of NSCLC were searched in PubMed, Cochrane Library, Web of science, EMbase, China National Knowledge Infrastructure, Wanfang, VIP database and SinoMed. The retrieval time was up to December 03, 2022. ROB2 was used to evaluate publication bias, and Stata16 was used for network meta-analysis.
A total of 14 studies involving 921 patients were included. The results of network Meta-analysis showed that the effect of acupuncture combined with chemotherapy was better than that of chemotherapy (RR = 1.28, 95%CI (1.04,1.58), P < .0001). The effect of acupuncture combined with chemotherapy was better than that of chemotherapy in improving KPS score (MD = 9.01, 95%CI (3.35,14.67), P < .0001). The safety of acupuncture combined with chemotherapy (RR = 0.35, 95%CI (0.15,0.83), P < .0001) was better than that of chemotherapy.
Acupuncture combined with chemotherapy has the best comprehensive effect.
通过网络荟萃分析比较不同针灸和艾灸方法的优缺点，以找出非小细胞肺癌（NSCLC）辅助化疗的最佳针灸和艾灸方案。
在 PubMed、Cochrane 图书馆、Web of science、EMbase、中国知网、万方、维普数据库和 SinoMed 中检索针灸辅助化疗治疗 NSCLC 的随机对照试验。检索时间截至 2022 年 12 月 03 日。使用 ROB2 评估发表偏倚，并使用 Stata16 进行网络荟萃分析。
共纳入 14 项研究，涉及 921 例患者。网络荟萃分析结果显示，针灸联合化疗的疗效优于单纯化疗（RR=1.28，95%CI（1.04，1.58），P<.0001）。针灸联合化疗在改善 KPS 评分方面的疗效优于单纯化疗（MD=9.01，95%CI（3.35，14.67），P<.0001）。针灸联合化疗的安全性优于单纯化疗（RR=0.35，95%CI（0.15，0.83），P<.0001）。
针灸联合化疗具有最佳的综合疗效。
