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阴茎龟头黑色坏死伴钙化防御:病例报告。

Black necrosis of the glans penis associated with calciphylaxis: A case report.

机构信息

Department of Emergency Medicine, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan Province, China.

出版信息

Medicine (Baltimore). 2023 Oct 20;102(42):e35609. doi: 10.1097/MD.0000000000035609.

DOI:10.1097/MD.0000000000035609
PMID:37861559
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10589551/
Abstract

RATIONALE

Calciphylaxis, known as calcific uremic arteriolopathy, is a rare cause of dry gangrene. Despite an increase in the clinical recognition of demographic characteristics and risk factors associated with calciphylaxis, it remains a poorly understood disease with high mortality.

PATIENT CONCERNS AND DIAGNOSES

We present a 45-year-old man, who was diagnosed with calciphylaxis disease, with a history of diabetes mellitus, end-stage renal disease and cirrhosis with a half-month evolution of painful dry gangrene on his glans penis and scrotum. The patient also presented with gangrene of fingers.

INTERVENTIONS AND OUTCOMES

The patient and his family opted for palliative care. However, he died eventually.

LESSONS

This case contributed to the current understanding of calciphylaxis. Since no standard treatment is available and the prognosis remained poor, early, and accurate diagnosis of calciphylaxis is important. We here report the current case and provide data for the diagnosis and treatment of this kind of disease.

摘要

理由

钙化防御,又称钙化尿毒症性小动脉病,是干性坏疽的一个罕见病因。尽管人们越来越认识到与钙化防御相关的人口统计学特征和危险因素,但该病仍然知之甚少,死亡率很高。

患者关注和诊断

我们介绍了一位 45 岁的男性患者,他患有钙化防御疾病,有糖尿病、终末期肾病和肝硬化病史,半个月前出现阴茎头部和阴囊疼痛性干性坏疽。患者还出现了手指坏疽。

干预措施和结果

患者及其家属选择了姑息治疗。但最终,他还是去世了。

经验教训

这个病例有助于加深对钙化防御的认识。由于没有标准的治疗方法,预后仍然很差,因此早期、准确的钙化防御诊断很重要。我们在此报告目前的病例,并为这种疾病的诊断和治疗提供数据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67ae/10589551/24d0da35afe4/medi-102-e35609-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67ae/10589551/b588127778c7/medi-102-e35609-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67ae/10589551/24d0da35afe4/medi-102-e35609-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67ae/10589551/b588127778c7/medi-102-e35609-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67ae/10589551/24d0da35afe4/medi-102-e35609-g002.jpg

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Black necrosis of the glans penis associated with calciphylaxis: A case report.阴茎龟头黑色坏死伴钙化防御:病例报告。
Medicine (Baltimore). 2023 Oct 20;102(42):e35609. doi: 10.1097/MD.0000000000035609.
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