Srimati Kanuri Santhamma Center for Vitreoretinal Diseases, Anant Bajaj Retina Institute, Kallam Anji Reddy Campus, L V Prasad Eye Institute, L V Prasad Marg, Banjara Hills, Hyderabad, Telangana, 500 034, India.
Standard Chartered - LVPEI Academy for Eye Care Education, L V Prasad Eye Institute, Hyderabad, Telangana, India.
Graefes Arch Clin Exp Ophthalmol. 2024 Feb;262(2):441-448. doi: 10.1007/s00417-023-06274-z. Epub 2023 Oct 20.
Outcomes of retinal detachment (RD) have been discussed in detail in many reports of patients with retinitis pigmentosa (RP). This study tries to understand the outcomes of vitreoretinal (VR) surgery for indications other than RD in the eyes with RP.
This is a retrospective study that includes clinical data from January 2013 to December 2021. Patients with RP who were treated with a VR surgical intervention were included in the study. The primary outcome of the study was to assess the changes in best-corrected visual acuity.
Forty-four eyes of 40 patients with RP were included in the study. Nearly half of the eyes (43%, 19/44) presented from 1 month to 1 year after the onset of diminished vision, with or without floaters. The mean ± standard deviation (SD) best-corrected visual acuity (BCVA) at presentation was 1.30 ± 0.79 logMAR (20/400 ± 20/125). The major surgical indications were vitreous opacities (43.2%, 19/44) and subluxated/dislocated cataractous lenses (25%, 11/44). The median follow-up duration was 8 months (interquartile range (IQR): 1.5-27). Approximately 77% (34/44) of the eyes had improvement in vision. The mean postoperative BCVA at the last follow-up was 0.95 ± 0.73 logMAR (p-value: 0.03).
Most eyes with RP recovered well after VR surgical interventions, with short-term improvements in visual acuity. It may be crucial to address the vitreous opacities and membranes as they hinder the residual central island of vision in RP. However, appropriate counselling is required regarding the progressive nature of retinal neuronal degeneration.
视网膜脱离（RD）的结果在许多关于色素性视网膜炎（RP）患者的报告中都有详细讨论。本研究试图了解 RP 眼中除 RD 以外的适应证行玻璃体视网膜（VR）手术的结果。
这是一项回顾性研究，纳入了 2013 年 1 月至 2021 年 12 月的临床数据。纳入了接受 VR 手术干预的 RP 患者。本研究的主要结局是评估最佳矫正视力（BCVA）的变化。
研究纳入了 40 例患者的 44 只眼。近一半的眼（43%，19/44）在视力下降后 1 个月至 1 年内出现，伴有或不伴有漂浮物。就诊时平均标准差（SD）最佳矫正视力（BCVA）为 1.30 ± 0.79 logMAR（20/400 ± 20/125）。主要手术适应证为玻璃体混浊（43.2%，19/44）和晶状体半脱位/脱位（25%，11/44）。中位随访时间为 8 个月（四分位距（IQR）：1.5-27）。约 77%（34/44）的眼视力改善。末次随访时平均术后 BCVA 为 0.95 ± 0.73 logMAR（p 值：0.03）。
RP 患者行 VR 手术后大多视力恢复良好，短期视力提高。解决玻璃体混浊和膜可能很重要，因为它们会阻碍 RP 中残余的中央岛状视力。然而，需要对视网膜神经元变性的进行性进行适当的咨询。
