Jindal A, Pathengay A, Mithal K, Chhablani J, Pappuru R R, Flynn H W
GMRV Campus, Visakhapatnam, L V Prasad Eye Institutes, India.
Nepal J Ophthalmol. 2014 Jan;6(11):98-101. doi: 10.3126/nepjoph.v6i1.10779.
Brilliant blue G is a new dye used for staining the internal limiting membrane to ease its peeling in cases like a macular hole.
Three patients presented with full-thickness idiopathic macular hole. They underwent pars planavitrectomy, Brilliant Blue G (BBG) stained internal limiting membrane peeling and fluid gas exchange.
Postoperatively,the macular hole closed but foveal thinning and perifoveal hyperpigmentation presumably due to BBG toxicity were observed in all three patients. All of them had a subnormal final best corrected visual acuity.
This case series highlights the unusual occurrence of macular toxicity following brillantblue G-assisted macular hole surgery.
亮蓝G是一种新型染料，用于在黄斑裂孔等病例中对视网膜内界膜进行染色，以便于其剥离。
三名患者患有全层特发性黄斑裂孔。他们接受了玻璃体切除术、亮蓝G（BBG）染色的视网膜内界膜剥离及液气交换。
术后，黄斑裂孔闭合，但在所有三名患者中均观察到了可能由于BBG毒性导致的黄斑变薄和黄斑周围色素沉着。他们所有人的最终最佳矫正视力均低于正常水平。
本病例系列突出了亮蓝G辅助黄斑裂孔手术后黄斑毒性这一不寻常的发生情况。
