Tecnológico Nacional de México/Instituto Tecnológico de Tepic, Laboratorio Integral de Investigación en Alimentos, Av. Tecnológico # 2595, Col. Lagos del country, C.P. 63175, Tepic, Nayarit, Mexico.
Facultad de Ingeniería, Universidad Autónoma de Querétaro, Campus Aeropuerto, Centro Universitario, Cerro de las Campanas, C.P. 76010, Santiago de Querétaro, Querétaro, Mexico.
Anal Biochem. 2024 Oct;693:115600. doi: 10.1016/j.ab.2024.115600. Epub 2024 Jul 2.
Foodborne pathogens are a grave concern for the for food, medical, environmental, and economic sectors. Their ease of transmission and resistance to treatments, such as antimicrobial agents, make them an important challenge. Food tainted with these pathogens is swiftly rejected, and if ingested, can result in severe illnesses and even fatalities. This review provides and overview of the current status of various pathogens and their metabolites transmitted through food. Despite a plethora of studies on treatments to eradicate and inhibit these pathogens, their indiscriminate use can compromise the sensory properties of food and lead to contamination. Therefore, the study of detection methods such as electrochemical biosensors has been proposed, which are devices with advantages such as simplicity, fast response, and sensitivity. However, these biosensors may also present some limitations. In this regard, it has been reported that nanomaterials with high conductivity, surface-to-volume ratio, and robustness have been observed to improve the detection of foodborne pathogens or their metabolites. Therefore, in this work, we analyze the detection of pathogens transmitted through food and their metabolites using electrochemical biosensors based on nanomaterials.
食源性病原体是食品、医疗、环境和经济领域的严重关切。它们易于传播且对治疗（如抗菌剂）具有抗性，这使得它们成为一个重要的挑战。受这些病原体污染的食物会被迅速拒绝，如果摄入，可能会导致严重疾病甚至死亡。本综述概述了通过食物传播的各种病原体及其代谢物的现状。尽管有大量关于消除和抑制这些病原体的治疗方法的研究，但它们的滥用会损害食物的感官特性并导致污染。因此，已经提出了电化学生物传感器等检测方法的研究，电化学生物传感器是一种具有简单、快速响应和灵敏度等优点的设备。然而，这些生物传感器也可能存在一些局限性。在这方面，据报道，具有高导电性、大表面积与体积比和稳健性的纳米材料已被观察到可提高食源性病原体或其代谢物的检测。因此，在这项工作中，我们分析了基于纳米材料的电化学生物传感器对通过食物传播的病原体及其代谢物的检测。
