Department of Radiology, ASST Spedali Civili, Brescia, Italy.
Department of Advanced Biomedical Sciences, University of Naples Federico II, Via Pansini 5, 80131, Naples, Italy.
Clin J Gastroenterol. 2024 Feb;17(1):112-117. doi: 10.1007/s12328-023-01871-1. Epub 2023 Oct 21.
Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver, with several histological variants being reported in literature. Hereby, we describe a case of a 77-year-old man with chronic liver disease referred to our department for performing a computed tomography (CT) due to a liver mass discovered at an abdominal ultrasound follow-up. At CT, a large, ill-defined lesion in the third hepatic segment was detected, characterized by progressive and delayed enhancement with minimal retraction of the hepatic capsule, associated with perihepatic adipose tissue inhomogeneity, mimicking a cholangiocarcinoma. At histopathological evaluation, the lesion turned out to be an HCC with lymphoepithelioma-like component and osteoclastic-like giant cells. This report focuses on the clinicopathological and radiological features of this unique case.
肝细胞癌 (HCC) 是肝脏最常见的原发性恶性肿瘤，文献中报道了几种组织学变异型。在此，我们描述了一例 77 岁男性慢性肝病患者，因腹部超声随访时发现肝内肿块，来我科行计算机断层扫描 (CT)。CT 显示第三肝段有一个大的、边界不清的病变，表现为渐进性和延迟性增强，肝包膜轻微回缩，伴有肝周脂肪组织不均匀，类似于胆管细胞癌。组织病理学评估显示病变为伴有淋巴上皮样成分和破骨细胞样巨细胞的肝细胞癌。本报告重点介绍了这个独特病例的临床病理和影像学特征。
