Department of Nursing, Chengdu University of Traditional Chinese Medicine, Chengdu, 610072, China.
Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.
Aging Clin Exp Res. 2023 Dec;35(12):2861-2871. doi: 10.1007/s40520-023-02587-5. Epub 2023 Oct 21.
To provide a summary of the available evidence concerning prevalence and risk factors of frailty in elderly patients with CHF.
PubMed, Embase, Web of Science, CINAHL, The Cochrane Library, China National Knowledge Infrastructure Database (CNKI), Chinese Biomedical Database (Sinomed), Weipu Database (VIP), and Wanfang database were searched from inception to July 2023. This study strictly followed the PRISMA guidelines. The quality of the included studies was rated by the Agency for Healthcare and Research and Quality and the Newcastle-Ottawa Scale.
A total of 21 original studies were included, involving 4,797 patients. Meta-analysis results showed that the prevalence of frailty in older patients with heart failure was 38% (95%CI: 0.32-0.44). Age, cardiac function grading, left atrial diameter, left ventricular ejection fraction, hemoglobin, polypharmacy, BNP, nutritional risk, and hospitalization day are the influential factors of frailty in older patients with CHF.
The prevalence of frailty in older patients with CHF is high, and clinical medical personnel should identify and intervene early to reduce or delay the frailty in older patients with CHF as much as possible.
总结心力衰竭老年患者衰弱的患病率和相关危险因素的现有证据。
检索 PubMed、Embase、Web of Science、CINAHL、The Cochrane Library、中国知网数据库（CNKI）、中国生物医学文献数据库（Sinomed）、维普数据库（VIP）和万方数据库，检索时间均从建库至 2023 年 7 月。本研究严格遵循 PRISMA 指南。采用美国卫生保健研究与质量局和纽卡斯尔-渥太华量表评价纳入研究的质量。
共纳入 21 项原始研究，涉及 4797 例患者。Meta 分析结果显示，心力衰竭老年患者衰弱的患病率为 38%（95%CI：0.32-0.44）。年龄、心功能分级、左心房直径、左心室射血分数、血红蛋白、联合用药、BNP、营养风险和住院天数是心力衰竭老年患者衰弱的影响因素。
心力衰竭老年患者衰弱的患病率较高，临床医务人员应尽早识别并进行干预，以尽可能减少或延缓心力衰竭老年患者的衰弱。
