Tanaka H, Kanosue K, Nakayama T, Shen Z
Physiol Behav. 1986;38(1):145-51. doi: 10.1016/0031-9384(86)90145-9.
During heat stress, rats extend their body and spread saliva onto their body surfaces (grooming) for evaporative heat loss in addition to tail vasodilation. We investigated the effects of changing hypothalamic (Thy) and ambient (Ta) temperatures on these thermoregulatory responses. The higher the Ta, the lower the Thy at which grooming started when Ta was changed from the thermoneutral zone (24 degrees C) to 28-40 degrees C. At any Ta grooming was induced only when the posterior hypothalamic region (PH) was warmed by implanted diathermy. Grooming was more strongly induced at a Ta of 28 degrees C than at 24 degrees C. At a Ta of 32 degrees C, PH warming evoked body extension as well, decreasing the duration of grooming as compared to that at 28 degrees C. Warming the preoptic area and anterior hypothalamus induced body extension and tail vasodilation regardless of Ta. The data suggest that grooming was induced by integrated temperature signals from the PH and from the peripheral skin.
在热应激期间，大鼠除了通过尾部血管舒张散热外，还会伸展身体并将唾液涂抹在体表（梳理毛发）以实现蒸发散热。我们研究了改变下丘脑温度（Thy）和环境温度（Ta）对这些体温调节反应的影响。当Ta从热中性区（24℃）变化到28 - 40℃时，Ta越高，开始梳理毛发时的Thy越低。在任何Ta下，只有当通过植入透热疗法使下丘脑后部区域（PH）升温时才会引发梳理毛发行为。在28℃时比在24℃时更强烈地引发梳理毛发行为。在32℃时，PH升温也会引起身体伸展，与28℃时相比，梳理毛发的持续时间缩短。无论Ta如何，视前区和下丘脑前部升温都会引起身体伸展和尾部血管舒张。数据表明，梳理毛发行为是由来自PH和外周皮肤的综合温度信号诱导产生的。
