松鼠猴的血管运动阈值：中枢和外周温度的影响

Vasomotor thresholds in the squirrel monkey: effects of central and peripheral temperature.

作者信息

Lynch W C, Adair E R, Adams B W

出版信息

J Appl Physiol Respir Environ Exerc Physiol. 1980 Jan;48(1):89-96. doi: 10.1152/jappl.1980.48.1.89.

DOI:10.1152/jappl.1980.48.1.89

Abstract

Six squirrel monkeys (Saimiri sciureus) participated in two ex,eriments examining how central (preoptic/anterior hypothalamic, Tpo) and peripheral (ambient, Ta, or mean skin, Tsk) temperatures influence peripheral vasomotion. In the first experiment, four monkeys with unilateral preoptic thermodes were exposed to a wide range of central (23 degrees C less than Tpo less than 44 degrees C) and peripheral (10 degrees C less than Ta less than 38 degrees C) temperatures. Results indicated that the skin of both tail and foot vasodilates at discrete but unique Ta thresholds (Tpo congruent to 39 degrees C) and that raising Tpo lowers these thresholds. In the second experiment, results from two monkeys implanted with bilateral thermodes surrounding the preoptic area replicated those of experiment 1. Subsequent tests with these two monkeys on the quantitative interaction between central and peripheral temperatures indicated that the dilation threshold is approximately a linear function of Tpo and Tsk. These effects are related to the interaction between central and peripheral inputs to the thermoregulatory system.

摘要

六只松鼠猴（松鼠猴属）参与了两项实验，研究中枢（视前区/下丘脑前部，Tpo）和外周（环境温度，Ta，或平均皮肤温度，Tsk）温度如何影响外周血管运动。在第一个实验中，四只单侧视前区植入温度传感器的猴子被暴露于广泛的中枢温度（23℃＜Tpo＜44℃）和外周温度（10℃＜Ta＜38℃）范围内。结果表明，尾巴和足部皮肤在离散但独特的Ta阈值（Tpo≈39℃）时血管舒张，并且提高Tpo会降低这些阈值。在第二个实验中，两只视前区周围植入双侧温度传感器的猴子的实验结果重复了实验1的结果。随后对这两只猴子进行的关于中枢和外周温度定量相互作用的测试表明，舒张阈值大约是Tpo和Tsk的线性函数。这些效应与体温调节系统的中枢和外周输入之间的相互作用有关。